Path: utzoo!utgpu!jarvis.csri.toronto.edu!rutgers!cs.utexas.edu!turpin From: turpin@cs.utexas.edu (Russell Turpin) Newsgroups: sci.bio Subject: Re: What's the Why and How of Mosquito Bites? Summary: ARF is confused (again). Message-ID: <6735@cs.utexas.edu> Date: 21 Aug 89 23:08:44 GMT References: <5399@mtgzy.att.com> <4948@tank.uchicago.edu> <9263@chinet.chi.il.us> <9309@chinet.chi.il.us> Organization: U. Texas CS Dept., Austin, Texas Lines: 44 ARF says: > I think we all know that "real", to a scientist, means the > results of rigorous, controlled experimentation, the results > of which lead to a conclusion. > > > As a molecular biologist, I am quite impressed by what one > > can learn from epidemiology... > > As a scientist, I am more impressed by the results of > controled experiments. If you can't or won't do them, that > is your privilege, but you can not manufacture the data and > call it SCIENCE. Who, pray tell, is manufacturing data? The major fabrication I see is the specious implication that something is scientific evidence only if it is garnered by controlled experiment, and that observation and statistical analysis do not count. Since Galen, careful observation has been a cornerstone of medical science, and it remains so today, though our methodological requirements have been refined over the centuries. There are many sciences in which certain crucial evidence can only be gathered by observation, because controlled experimentation is impossible. These include astronomy -- we cannot create stars in the laboratory; geology -- there is only one earth to study; and biology -- the epidemiology of every disease is observed only, since no one would purposely introduce a disease into a control population to see if its spread matches what is predicted by theory, not to mention the fact that one cannot arbitrarily prepare test populations. In all of these, laboratory experiments complement observation. The physical theories underlying stellar evolution and geological processes are tested by thousands of experiments. The biological and chemical mechanisms of many disease organisms, including HIV, are studied both in vitro and in animal hosts. Perhaps it is because ARF is confused about the nature of scientific work that he is so suspicious of the way scientists are studying AIDS. There have been no controlled experiments to test whether syphillis can be transmitted by mosquito, or whether typhus can be spread by air droplets as well as lice. If ARF is going to ramble on, perhaps these will provide him more fodder. Russell