Path: utzoo!attcan!uunet!cs.utexas.edu!usc!ucla-cs!chet@retix.retix.COM From: chet@retix.retix.COM (Chet Mazur) Newsgroups: sci.med.aids Subject: Re: F->M HIV transfer Message-ID: <29423@shemp.CS.UCLA.EDU> Date: 22 Nov 89 00:28:39 GMT References: <29307@shemp.CS.UCLA.EDU> Sender: news@CS.UCLA.EDU Reply-To: chet%retix@uunet.UU.NET (Chet Mazur) Organization: Retix, Santa Monica CA Lines: 11 Approved: aids@cs.ucla.edu Archive-number: 1508 The risk from M->F x'fer seems to be the same as for F->M. This is based on research in Africa, where the majority of PWA's are heterosexual and you don't see a disproportionate amount of females infected (implying M->F is riskier) or vis-versa. As for being uncircumcised, this does put you at greater risk (again based on African research).... The reason is not known (yet) but it is suspected that the unretracted foreskin provides a great place for the virus to live (warm, dark, moist). Also the "un-cut" penis is much more sensitive and therefore subject to abrasion; with this allowing transmission.