Xref: utzoo ont.events:1393 sci.math.stat:996 Newsgroups: utstat.general,ont.events,sci.math.stat Path: utzoo!utstat!ruth From: ruth@utstat.uucp (Ruth Croxford) Subject: Statistics Colloquium: Scott Zeger - GLM with Dependent Responses Message-ID: <1989Nov28.000737.5687@utstat.uucp> Organization: Statistics, U. of Toronto Distribution: ont Date: Tue, 28 Nov 89 00:07:37 GMT Expires: 8-dec-1989 Colloquium, University of Toronto, Dept. of Statistics Topic: Generalized Linear Models with Dependent Responses Speaker: Scott L. Zeger, Johns Hopkins University Date: Thursday, December 7, 1989 4:00 - 5:00 Place: Room 1085, Sidney Smith Hall, 100 St George Street, U of T Abstract: Generalized linear models have unified the approach to regression for a wide variety of discrete, continuous and censored response variables which can be assumed to be independent across experimental units. In applications such as longitudinal studies, genetic studies of families and survey sampling, observations may be obtained in clusters. Responses from the same cluster can not be assumed to be independent. With linear models, correlation has been effectively modelled by assuming there are cluster-specific coefficients (random effects) which derive from an underlying mixing distribution. Extensions of generalized linear models to include random effects has thus far been hampered by the need for higher order integration to evaluate likelihoods. In this talk, we cast the generalized linear random effects model in a Bayesian framework and use a recent Monte Carlo method, the Gibb's sampler, to overcome the current numerical limitations. The resulting algorithm is flexible to easily accommodate changes in the number of random effects and in their assumed distribution. The methodology is illustrated through an analysis of infectious disease data. ------- Coffee and tea will be served in the De Lury Lounge (SS6006) at 3:30 p.m. Brought to you by Super Global Mega Corp .com