Path: utzoo!attcan!uunet!munnari.oz.au!bruce!lloyd From: lloyd@bruce.OZ (lloyd allison) Newsgroups: bionet.molbio.evolution Subject: Re: How to compare trees Message-ID: <1950@bruce.OZ> Date: 19 Mar 90 00:32:04 GMT References: <3067.2602a4ec@bmc.uu.se> Organization: Monash Uni. Computer Science, Australia Lines: 20 Mats.Sundvall@bmc.uu.se writes: >Does somebody out there have some comments on how to compare evolutionary >trees calculated by maximum parsimony algorithms. If I generate one The best approach I know of as yet is the maximum likelihood method of Joseph Felsenstein Dept of Genetics, Uni of Washington, Seattle eg "Inferring Evolutionary Trees from DNA Structures" Statistical Analysis of DNA Sequence Data (ed) B. S. Weir, Marcel Dekker inc 1983 p133-150 This has excellent statistical validity. It may not be practical if your tree is very big. JF distributes a package containing several tree building methods for free. This includes a parsimony method and a M.L. method. Lloyd Allison, Computer Science, Monash University, AUSTRALIA 3168 zzz