Path: utzoo!utgpu!news-server.csri.toronto.edu!mailrus!cs.utexas.edu!usc!ucla-cs!kwmc@cbnewsj.att.com From: kwmc@cbnewsj.att.com (Kenneth G Cochran) Newsgroups: sci.med.aids Subject: Re: Cure for AIDS Summary: treatment was used during WWII for syphillis Message-ID: <36002@shemp.CS.UCLA.EDU> Date: 5 Jun 90 14:09:51 GMT References: <35945@shemp.CS.UCLA.EDU> Sender: news@CS.UCLA.EDU Organization: AT&T Bell Laboratories Lines: 26 Approved: ddodell@stjhmc.fidonet.org (David Dodell) Note: Copyright 1990 by Daniel R. Greening. Permission granted for Note: non-commercial reproduction. Archive-number: 2137 Hyperthermia, which I believe is the technical term for elevated body temperatures was used during World War II before the advent of penicillin as a treatment for syphillis. The idea is that if the organism dies at temperature X and the patient dies at temperature Z, then elevating the patients temperature to Y where X < Y < Z can potentially eliminate the organism. There is some evidence that HIV can hide in the brain out of contact with the blood, so I would doubt if just heating the blood would effect a permanent cure. Thus techniques for raising the whole body temperature are desired. During WWII two techniques were used that I know of 1) dripping modified typhoid "bugs" into the patient in a saline drip inducing high fever, and carefully controlling the rate of infusion to maintain temperature at Y. 2) imersing the patient in in a special 'bath'. (Kettering Hypertherm) this latter technique I believe was so uncomfortable that anethesia was required. How do I know alll this ? ... My father was a doctor who used these techniques during WWII and is researching possible refinements of the process for AIDS treatment in Britain. Of course I have probably missed a few salient points and used amateur terminology, but the underlying principles should be clear. Ken Cochran att!mtdca!kwmc