Path: utzoo!utgpu!watserv1!watmath!uunet!snorkelwacker!bionet!yalevm.bitnet!GENWPA From: GENWPA@yalevm.bitnet ("William P. Alles") Newsgroups: bionet.jobs Subject: (none) Message-ID: <9007080321.AA06778@genbank.bio.net> Date: 8 Jul 90 03:22:54 GMT Sender: daemon@genbank.BIO.NET Lines: 161 I am currently seeking employment as a programmer in a biomedical research environment. I have had 8 years experience as a programmer (using the Basic, Fortran, C, and Assembly languages (Northstar Horizon (Z80-CP/M), IBM PC, PDP 11-73 (RT-11, RSX-11M), and VAX/VMS) in a biomedical research environment; additionally, I have had two years experience maintaining the Human Genome Workshop database (IBM VM/CMS, Spires DBMS). Relocation to another area is a not concern. =============================================================================== William P. Alles 165 Monticello Drive Branford, CT 06405-4166 Home Phone: (203) 483-0443 Work Phone: (203) 786-5566 Bitnet: GENWPA@YALEVM Work Experience October, 1988 to Present: Programmer/Database Manager, Department of Biology, Yale University, and the Howard Hughes Medical Institute, Human Gene Mapping Library, New Haven CT Responsible for the design and maintenance of the human genetics database used during, and since, the 10th International Workshop on Human Gene Mapping (HGM10), held in New Haven in June 1989; responsible for maintaining links to the other genetics databases maintained by the HGML. Developed a C language, PC-based program to allow for the searching and updating of a distributed form of the Workshop database. Coordinated the publication of the HGM10 proceedings, an 1150 page, camera-ready copy published as volume 51 of Cytogenetics and Cell Genetics. Designed a Fortran language, PC-based program to allow the electronic submission of abstracts and supporting data for the Workshop. December, 1986 to October, 1988: Software Systems Programmer, Biomedical Computing Unit, Yale University, New Haven, CT Developed data collection and analysis packages for use on Northstar Horizon, IBM PC-XT, DEC PDP 11-73, VaxStation and MicroVax microcomputers, used by medical researchers in physiology and neurophysiology. Responsible for the maintenance of the genetics databases (GenBank, EMBL, NAQ, PIR, Swiss Protein) on VAX 760 and VAX 8800, for use by medical researchers. Primary functions included: Data management (database installation, backups, rebuilds); Software management (installation and maintenance of GCG, PIR and Staden software packages, customized modification this software, development of new software tools to access the databases); User services (writing user documentation and instruction of researchers on the use of the computer, software and databases). Management of a teaching lab in the Yale Medical School. Primary functions included: Hardware Management (IBM PC-AT); Software Management (WordPerfect, Microsoft Word, Lotus-123, Notebook II, Turbo Pascal, PC-Manager); User services (instruction of medical students on the use of PCs and software). May, 1984 to December, 1986: Associate in Research I, Department of Physiology, Yale University, New Haven, CT Responsible for the management of the laboratory, including requistion/ purchase of drugs, radioactive isotopes, animals, chemicals and general supplies used in the lab., and computer hardware/software purchases, installation, and maintenance. Developed data collection and analysis packages on DEC PDP 11-73, IBM PC- AT, and Northstar Horizon microcomputers, for use in physiological research. Developed plotting/graphical software for use on Hewlett Packard and Houston Instruments plotters. Performed many of the experiments conducted in the laboratory, analyzed the data collected, and assisted in the writing of journal articles and grant proposals. September, 1982 to May, 1984: Assistant in Research II, Department of Physiology, Yale University, New Haven, CT Performed experiments and analysis of the data collected by the laboratory; developed programs used to collect and analyze data on DEC 11-73 and Northstar Horizon microcomputers. May, 1980 to September, 1982: Assistant in Research I, Department of Physiology, Yale University, New Haven, CT Assisted in experiments performed by the laboratory; debugged and improved upon existing programs used to collect and analyze data on a Northstar Horizon microcomputer. Education Fall, 1984 University of New Haven, New Haven, CT Courses: Fortran, general MIS. 09/73-05/77 State University of New York at Albany, Albany, NY M.S. Program, Neurobiology (ABD) 09/73-05/77 B.A., University of Pennsylvania, Philadelphia, PA Major: Biology Honors: General Honors Program, Benjamin Franklin Scholar 09/69-06/73 N.Y. State Regents Diploma, Bay Shore High School, Bay Shore, NY Honors: National Merit Semi-finalist, National Honor Society member, New York State Regents Scholarship Hardware Experience IBM: IBM 3088 mainframe, PS2 50/60/70, PC-AT, PC-XT DEC: VAX 8800, VAX 760, Vaxstation, MicroVax, PDP 11-73 Other: Northstar Horizon (Z80 based microcomputer) Software Experience Operating Systems: VM/CMS, VMS, RT-11, RSX-11M, DOS (2.0 - 3.3), CP/M DBMS/Spreadsheet: SPIRES, Lotus-123, dBASE, Paradox Word Processing: Wordperfect (V. 4.2, 5.0, 5.1), Wordstar Languages: Turbo C, Turbo Pascal, Microsoft Fortran, Fortran IV, Fortran 77, VAX Fortran, IBM Basic, Horizon Basic, DEC Basic, DEC Basic-23, VAX Assembly, Z-80 Assembly, APL Miscellaneous: DEC Labstar, VAX/VMS RMS routines, GCG Software, REXX Publications Mador ML, Cavanaugh ML, Chan HS, Alles WP, Hawley ME, Miller RL, Schiff GL, Ruddle FH, Kidd KK. The HGM10 information management system. Cytogenet. Cell Genet. 1989, 51(1-4):3-7. Miller RL, Chan HS, Cavanaugh ML, Alles WP, Mador ML, Kidd KK. EDIT10: a database interface for HGM10. Cytogenet. Cell Genet. 1989, 51(1-4):9-10. Lewis SA, Alles, WP. Urinary kallikrein: a physiological regulator of epithelial Na+ absorption. Proc. Natl. Acad. Sci. U.S.A. 1986 July, 83(14):5345-8. Sandle GI, Wills NK, Alles WP, Binder HJ. Electrophysiology of the human colon: evidence of segmental heterogeneity. Gut 1986 September, 27(9):999-1005. Hanrahan JW, Alles WP, Lewis SA. Single anion channels in basolateral membrane of a mammalian tight epithelium. Proc. Natl. Acad. Sci. U.S.A. 1985 November, 82(22):7791-5. Wills NK, Alles WP, Sandle GI, Binder HJ. Apical membrane properties and amiloride binding kinetics of the human descending colon. Am. J. Physiol. 21984 December, 47(6 pt 1):G749-57. Stetson DL, Lewis SA, Alles WP, Wade JB. Evaluation by capacitance measurements of antidiuretic hormone induced membrane area changes in toad bladder. Biochim. Biophys. Acta 1982 July, 689(2):267-74. References available on request. Salary history available on request.