Path: utzoo!utgpu!watserv1!watmath!uunet!bionet!VM.NRC.CA!DID1290 From: DID1290@VM.NRC.CA (Paul andrews) Newsgroups: bionet.jobs Subject: Permanent position Message-ID: <9008291451.AA03947@genbank.bio.net> Date: 29 Aug 90 14:50:50 GMT Sender: daemon@genbank.BIO.NET Lines: 160 Aug 29,1990 Bureau of Drug Research Health and Welfare Canada Tunney's Pasture Ottawa, Ontario, Canada K1A 0L2 I presently hold the position of National Science and Engineering Council Research Council Visiting Fellow at Health and Welfare Canada and am seeking employment. As a Canadian citizen under the terms of the US-Canada Free Trade Agreement, I am eligible for an H-1 or TC (Treaty Canada) visa allowing me to work in the U.S.A. During my research career I gained extensive experience in the HPLC and GC analysis of drugs and their metabolites, DNA-adducts, proteins and peptides, and mass spectrometry of polar biological compounds. I am also proficient in other chromatographic methods as well as techniques in inorganic analysis. Computers have played an important role in my research for data acquisition and telecommunications. I am familiar with PC/MS-DOS, Unix, and VM/CMS computer operating systems. My skills as an analytical chemist and my background in analytical toxicology, biochemistry and computer systems make me an ideal candidate for either a technical or managerial position. The following text is my resume which includes my E-mail address for the computer facility I use at the National Research Council in Ottawa, and a FAX number for the Bureau of Drug Research, Health and Welfare Canada. Thank you for your consideration in this matter. Paul Andrews, PhD NSERC Visiting Fellow ================================================================= ==== RESUME FOR PAUL JOHN ANDREWS PERSONAL DATA Address 2074 Carling Avenue, Ottawa, Ontario, Canada K2A 1G8. Birthdate June 16, 1954 Citizenship Canadian Phone Home:(613)729-8826. Work:(613)957-3506 E-Mail (Bitnet/Netnorth) DID1290@VM.NRC.CA FAX (613) 957-1907 EDUCATIONAL DATA 1987 PhD., Chemistry, McMaster University,Hamilton, Ontario, Canada. 1981 MSc., Analytical Toxicology, Queen's University, Kingston, Ontario, Canada. 1978 BSc., Chemistry, McMaster University, Hamilton, Ontario, Canada. HONOURS AND AWARDS 1973 Ontario Scholar 1978 Queen's Graduate Fellowship 1989 National Science and Engineering Research Council of Canada Visiting Fellow Award WORK EXPERIENCE 1989-Present National Science and Engineering Research Council of Canada Visiting Fellow, Bureau of Drug Research, Ministry of Health and Welfare, Tunney's Pasture, Ottawa, Ontario, Canada. 1987-1989 Post Doctoral Research Fellow, College of Pharmacy, Division of Medicinal Chemistry, University of Texas, Austin, Texas, USA. 1986 Lecturer, Mohawk College, Hamilton, Ontario, Canada. 1978-1986 Teaching assistant, McMaster University, Queen's University. 1977-1978 Summer research assistant, McMaster University. REFERENCES 1. Dr. Creed Abell, PhD., Henry M. Burlage Endowed Centennial Professor, College of Pharmacy, Division of Medicinal Chemistry, University of Texas at Austin, Austin, Texas, USA 78712. Phone:(512)471-5715. 2. Dr. Michael A. Quilliam, PhD., Associate Research Officer, Atlantic Research Laboratory, National Research Council, 1411 Oxford St., Halifax, Nova Scotia, Canada B3H 3Z1. Phone:(902)426-9736. 3. Dr. Brian Foster, PhD., Research Scientist, Bureau of Drug Research, Health and Welfare Canada, Sir Frederick Banting Building, Tunney's Pasture, Ottawa, Ontario, Canada K1A 0L2. Phone:(613)957- 3506. PROFESSIONAL ESSAY During my research career I have become proficient in the area of organic analytical chemistry with emphasis on trace analysis by GC, HPLC and mass spectrometry. I also developed computer skills for the acquisition and manipulation of experimental data. Currently, at Health and Welfare Canada, I am a member of the Biotechnology Section of the Bureau of Drug Research. My major responsibility is to conduct studies into the metabolism of a series of nitroimidazoles by fungi which have the unique ability to mimic mammalian metabolism. This study, which is funded by the US- FDA, will gain insight into the evaluation of the toxicity of protein-bound drug residues. Other regulatory duties include the assessment of federal IRAP grants and assisting in evaluating drug submissions. I am also responsible for coordinating the Bitnet/Internet/Netnorth newsgroups of interest to other scientists in the Health Protection Branch. My post-doctoral research centred on HPLC and mass spectrometric (probe and GC-MS) characterization of proteins, peptides and riboflavin analogues. Protein isolation and characterization techniques were developed for other members of my research group. I also aided in the drafting of several major research grant proposals. I was responsible for the acquisition, set up, and management of a Beckman System Gold HPLC system which was used for the computer control of other HPLC systems and detectors used in our laboratory. My familiarity with the "Intelligenetics" suite of molecular biology software played an important role in my research. My skills in telecommunications networks using TCP/IP and Telnet under TOPS-20, UNIX, and VM/CMS operating systems were important in my research. In order to improve my skills in computer programming I taught myself "C", a programming language, and expanded my knowledge of PC-DOS, UNIX, and IBM 3270 VM/CMS operating systems. Research for my PhD dealt with the isolation and characterization of adducts formed between DNA and the metabolites of nitrated aromatic hydrocarbons. I extensively investigated methods for the gentle derivatization and ionization of these nonvolatile, polar compounds by mass spectrometry. Some of the techniques used we EI, CI, FAB, GC-MS, and LC-MS. I learned to acquire and manipulate data using data analysis packages such as Lotus 1-2-3 and Excel. In my PhD courses I developed skills in solving non-routine analytical chemistry problems such as the analysis of inorganics and PAHs in oil sands. My MSc research involved the development of new extraction and derivatization methods for the GC and GC-MS analysis of alkaloids from a biological matrix. Graduate analytical chemistry courses allowed me to obtain hands-on experience in many inorganic and organic analytical methods such as GC, HPLC, and GC-MS. Experience gained in various laboratories has allowed me to become an expert in GC, HPLC and mass spectrometry, especially in the area of organic analytical chemistry. My skills in solving problems in many areas of analytical chemistry will be an asset to a firm interested in someone who can deal with situations that call for a wide range of problem solving abilities.