Path: utzoo!attcan!uunet!bionet!apple!julius.cs.uiuc.edu!wuarchive!zaphod.mps.ohio-state.edu!samsung!cs.utexas.edu!hellgate.utah.edu!linkers.med.utah.edu!linkers!launce From: launce@apollo.med.utah.edu (Launce Gouw) Newsgroups: bionet.software Subject: Re: Computational simulation of DNA melting Message-ID: Date: 12 Sep 90 17:41:51 GMT References: Sender: news@linkers.med.utah.edu (Netnews owner) Distribution: bionet Organization: University of Utah Lines: 32 In-reply-to: launce@apollo.med.utah.edu's message of 11 Sep 90 13:37:01 In article launce@apollo.med.utah.edu (Launce Gouw) writes: Newsgroups: bionet.software Path: linkers.med.utah.edu!linkers!launce From: launce@apollo.med.utah.edu (Launce Gouw) Sender: news@linkers.med.utah.edu (Netnews owner) Organization: University of Utah Distribution: bionet Date: 11 Sep 90 13:37:01 We're trying to get ahold of a program that predicts melting/denaturing conditions for DNA molecules of known sequence. In particular, we'd like the package of programs described by LS Lerman and K Silverstien in Met. Enzymol. 155: 482-501. We're interested in doing the denaturing gradient gel electrophoresis analysis as described by Myers, Maniatis and Lerman in the article following the one I've just mentioned. Stuff looks great, but those guys never left an address where they could be reached. Is it freeware? If not, how much is it? Can we get it thru an FTP site? Any info would be much appreciated. Thanks v. much in advance, L. Gouw Dept. of Human Genetics Univ. of Utah School of Medicine Salt Lake City, UT 84132 USA Oh yeah, I forgot to mention the names of the programs. They are: MELT, MU and SQHTX Thanks again.