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From: Wounded.Bird@f38.n135.z1.fidonet.org (Wounded Bird)
Newsgroups: sci.med.aids
Subject: Re: Negative Antibody tests
Message-ID: <39067@shemp.CS.UCLA.EDU>
Date: 18 Sep 90 14:15:45 GMT
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Note:	Copyright 1990 by Daniel R. Greening.  Permission granted for
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Archive-number: 2485


 >[I recieved this by mail from a correspondent who wishes to remain
 >anonymous, but agreed to let me forward his/her comments to the net -r]

 >> Subject: Re: Hot Blood
 >>
 >> ...
 >> Actually, there are plausible mechanism by which heat treatment could
 >> kill a cell containing an integrated but inactive provirus. In
 >> principle, the heat treatment (or some drug) could eliminate all
 >> infected cells and all live virus from a person. Unfortunately,
 >> the hyperthermia treatment does not seem to be effective after all.

Heat treatment sounds like a plausible "cure"  only if you are unaware of the 
following facts:

1> HIV is carried into the brain by monocytes/macrophages which carry the 
virus accross the blood-brain barrier. Once there HIV infects glial cells and 
endothelial cells. Glial cells provide structural support to nerve cells and 
help regulate the transfer of nutrients from blood vessels to nerve tissue and 
act like blood phagocytes by removing cellular debris from the brain. 
Endothelial cells line the blood vessels of the central nervous system.

2> HIV infects the Langerhans cells in our skin. Langerhans cells are part of 
the immune surveillance system. They send out long spindaly branches to trap 
foreign materials entering through the skin and then process them for 
presentation to nearby T cells.

3> HIV infects and reproduces in the bone marrow. NIAID researchers (Thomas M. 
Folks) demonstrated that cells in the marrow became "virtual bags of virus or 
wall-to-wall-virus."

4> HIV infects local tissues in the rectum and the female reproductive tract 
as well as in the intestines.

Soooo, UNLESS YOU ARE WILLING TO ACCEPT ONE WELL COOKED AND MOST PROBABLY DEAD 
PATIENT, HYPERTHERMIA IS NOT A PLAUSIBLE CURE FOR AIDS. MEDIUM RARE JUST WON'T 
CUT IT !

But, more importantly, if you are relying on the popular media, including 
major newspapers for your source of AIDS information, you are being terribly 
misinformed. As Randy Shilts explains, the '80's ushered in journalism by 
press release - blindly repeating what ever is fed to them. Investigative 
reporting, at least with AIDS, is rare or non-existant.

--  
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