Path: utzoo!attcan!uunet!nih-csl!helix.nih.gov From: csax@helix.nih.gov (Carl Saxinger) Newsgroups: bionet.jobs Subject: Postdoctoral offer Message-ID: <606@nih-csl.nih.gov> Date: 6 Nov 90 19:21:52 GMT Sender: news@nih-csl.nih.gov Organization: National Institutes of Health, Bethesda Lines: 42 Postdoctoral positions will be available in the Laboratory of Tumor Cell Biology (LTCB), Division of Cancer Etiology, Nationa Cancer Institute. The positions will commence during the summer of 1991, require degree documentation, three letters of reference and at least 3 to 4 months to process applications. Intramural Research Training Awards (IRTA) for U.S. citizens and NIH postdoctoral fellowships for foreign candidates are available. Applicants must have less than 3 years postdoctoral research experience. Beginning stipend is $25,000 to $28,000. Areas of investigation include development of HIV vaccine, mapping of helper and cytotoxic T cell epitopes, mapping of immuno- regulatory functions of HIV, HTLV & HHV6 viral proteins, mechanisms of receptor recognition and growth factor function by bioassay, and molecular modelling. This lab has developed an automated method and device for the design and synthesis of any 96 designated peptides in 96 well microtiter plates. The entire process is computer controlled and has been used to translate genomic sequences into "pepscan" overlapping peptide sequences and to generate variant length and amino acid substitution analogues, usually in less than 24 hour. The process has been successfully demonstrated by mapping peptide sequences to immnuodominant antibodies for HIV and HTLV human retroviral proteins, for lymphokines, and for cytokines. Also for cellular adhesion molecules and integrin receptors. This lab is also equipped with an ABI peptide synthesizer and has access to molecular biological support, patient materials, experimental animal facilities, and supercomputer facilities. For inquiries concerning these positions and the application of synthetic peptides in studies of immunology, virology and cell biology please contact Carl Saxinger, Ph.D. NIH, Bldg. 37, Rm 6C23 Bethesda, MD 20892 (301)480-1163 INTERNET: BITNET: Brought to you by Super Global Mega Corp .com