Path: utzoo!utgpu!watserv1!watmath!att!bu.edu!rpi!zaphod.mps.ohio-state.edu!wuarchive!uwm.edu!bionet!will From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human triosephosphate isomerase (TPI) gene, 5' end. Message-ID: Date: 8 Jan 91 15:49:10 GMT Sender: will@genbank.bio.net Distribution: bionet Lines: 58 Approved: lear@genbank.bio.net Checksum: 01021 3 LOCUS HUMTPIA 645 bp ds-DNA PRI 08-JAN-1991 DEFINITION Human triosephosphate isomerase (TPI) gene, 5' end. ACCESSION J04603 J04604 KEYWORDS triosephosphate isomerase. SOURCE Human DNA (library of T.Maniatis). ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 645) AUTHORS Boyer,T.G., Krug,J.R. and Maquat,L.E. TITLE Transcriptional regulatory sequences of the housekeeping gene for human triosephosphate isomerase JOURNAL J. Biol. Chem. 264, 5177-5187 (1989) STANDARD full staff_review REFERENCE 2 (sites) AUTHORS Boyer,T.G. and Maquat,L.E. TITLE Minimal sequence and factor requirements for the initiation of transcription from an atypical, TATATAA box-containing housekeeping promoter JOURNAL J. Biol. Chem. 265, 20524-20532 (1990) STANDARD full staff_review COMMENT Draft entry and printed sequence for [J. Biol. Chem. 264, 5177-5187 (1989)] kindly submitted by T.G. Boyer, 5-MAY-1989. FEATURES Location/Qualifiers misc_binding 458..463 /note="Sp1 binding site" misc_binding 470..475 /note="Sp1 binding site" misc_binding 484..489 /note="Sp1 binding site" misc_binding 488..493 /note="Sp1 binding site" misc_binding 515..520 /note="Sp1 binding site" misc_binding 543..548 /note="Sp1 binding site" misc_signal 569..575 /note="TATA box" precursor_RNA 596..>645 /note="TPI1 mRNA and introns" CDS 631..>645 /note="triosephosphate isomerase (EC 5.3.1.1) /hgml_locus_uid='LH0048S' /nomgen='TPI1' /map='12p13'" BASE COUNT 105 a 199 c 231 g 110 t ORIGIN Chromosome 12p13. 1 ctgcagttcc tgccaggcct tgccagccgg ggcgagggtt gggatgatcc tggcggccta 61 tgcctgtgtg ggctgcccct cccgctgtga accctgcatt tgtcccgcaa gttttcactc 121 aggtagactc cctgggtaca aagggtgcct gctcagcagt cgggcatgag ctgctccgat 181 gggcgaagga ggttgtctat tccacagttg gagagggccc tctctgccca gtgggcgatc 241 tgggctacgg ccaagttgcc accagctagt tccgcttgaa aaccacttct ggccccgtgg 301 gggactcaag cggtccaagc gagggttccc ctgagcgccg gagctcacag gtctcgcctt 361 gtcccgaaag cccccgcaat cgaggcggag gcgaccgagc ccccgactct cctagaacgt 421 tgccacaaga aggggaacgt cggaacagtg catcatcggg cggcggccgg ggcggcggca 481 ggagggcggg cggggggcag ggctccgggg gactgggcgg gccatggcgg aggacggcga 541 ggaggcggag ttccacttcg cggcgctcta tataagtggg cagtggccgg actgcgcgca 601 gacactgacc ttcagcgcct cggctcggcc atggcgccct ccagg //