Path: utzoo!utgpu!watserv1!watmath!uunet!wuarchive!zaphod.mps.ohio-state.edu!rpi!bu.edu!shelby!agate!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 Message-ID: Date: 16 Jan 91 13:06:35 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 51 Approved: lear@genbank.bio.net Checksum: 16004 3 LOCUS RATTRO08 88 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 7. ACCESSION L00379 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 8 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 88) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 78) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>88 /note="beta mRNA and intron" precursor_RNA <1..>88 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron F" intron <1..15 /note="trop1 intron F" exon 16..78 /note="skeletal muscle beta-tropomyosin, exon 7" exon 16..78 /note="embryonic fibroblast tropomyosin 1, exon 7" variation 74..74 /note="a in cDNA [J. Biol. Chem. 260, 14440-14445 (1985)],[Mol. Cell. Biol. 6, 3582-3595 (1986)]; g in DNA [Mol. Cell. Biol. 6, 3582-3595 (1986)] (table 1)" intron 79..>88 /note="beta intron G" intron 79..>88 /note="trop1 intron G" BASE COUNT 33 a 14 c 23 g 18 t ORIGIN About 150 bp after segment 7. 1 gtttgtctct taaagtattc caccaaagag gacaaatacg aagaagagat caaacttctg 61 gaggagaagc tgaaggaggt gagactac //