Path: utzoo!utgpu!news-server.csri.toronto.edu!bonnie.concordia.ca!uunet!ns-mx!iowasp.physics.uiowa.edu!maverick.ksu.ksu.edu!zaphod.mps.ohio-state.edu!wuarchive!mit-eddie!snorkelwacker.mit.edu!bloom-picayune.mit.edu!18.70.0.226!lfk From: lfk@eastman1.mit.edu (Lee F. Kolakowski) Newsgroups: bionet.software Subject: Message-ID: Date: 22 Jan 91 16:25:49 GMT Sender: news@athena.mit.edu (News system) Lines: 67 Cc: BROE@aardvark.ucs.uoknor.edu, FS300047@Sol.YorkU.CA, Ford@gdr.bath.ac.uk, Fuchs@EMBL.BITNET, GOLDMAN@ANCHOR.RUTGERS.EDU, JACKL%CAOS.CAOS.KUN.NL@CUNYVM.CUNY.EDU, JRR%NRCCAD.NRC.CA@mitvma.mit.edu, MIC232H@vaxc.cc.monash.edu.au, Richard James Tobias , SMITH%MCCLB0.MED.NYU.EDU@mitvma.mit.edu, TOLVANEN@cc.Helsinki.FI, TONY@wehi.dn.mu.oz.au, UDAA420@hazel.cc.kcl.ac.uk, UOG00035%VM.UoGuelph.CA@mitvma.mit.edu, ajp2o@crocus.medicine.rochester.edu, av8tr!elliston@uunet.uu.ne Organization: Mass. Inst. of Tech., Dept. of Chemistry Distribution: bionet Date: 23 Jan 91 10:59:02 Lines: 52 t, bairoch@cgecmu51.BITNET, bloom-beacon!rutgers!nwnexus.wa.com!farrah (Theresa Farrah), bryn@orchid.UCSC.EDU (Bryn Weiser - Bio. dept.), cmdsix@vaxa.weeg.uiowa.edu, compchem@gw.wmich.edu, cshort@NMSU.Edu, davison@uhnix2.uh.edu, gilbertd@silver.ucs.indiana.edu, gnu@toad.com, gwilliam@mrc-crc.ac.uk, jes@mbio.med.upenn.edu (Joe Smith), jkramer@umbio.miami.edu (Jack Kramer), kozar%CITIAGO.BITNET@mitvma.mit.edu (Lee G. Kozar), ljm@mayo.EDU (Larry Miller), macrakis@ri.osf.fr, model@ROCKY2.ROCKEFELLER.EDU, pauls @mrcvax.edinburgh.ac.uk, prasher@hyatt.whoi.edu (Doug Prasher), reisner@ee.su.oz.AU (Alex Reisner), roberts@CSHLAB.BITNET, rodrigol@ulrik.uio.no (Rodrigo Lopez), seqtest@wccf.mit.edu, templon@venus.iucf.indiana.edu (Jeffrey Templon), tobias@decpa.pa.dec.com, werner@helix.nih.gov (Werner Klee), wjb1@midway.uchicago.edu, prevelig.eastman1.mit.edu, atomeka@wccf.mit.edu Subject: ProSearch Version 1.23 for Prosite 6.0 The scripts for Prosite Pattern Database Searching are now available for anonymous FTP from mbio.med.upenn.edu (128.91.18.14) in /pub/ProSearch/*. There are several files for different machines. prosea12.zoo - a zoo archive for MSDOS prosearch1.2.dclshar - a VMS shell script prosearch1.2.shar.Z - a Unix Shell archive compressed prosea12.uue - a uuencode version of the zoo archive New items included in ProSearch 1.2: cregex.c - a c program to generate the regex file written by Jack Leunissen. tfd2prosite - a c program to translate the TFD database to Prosite format by Ranier Fuchs. tfdsearch - Scripts similar to those in ProSearch for searching the TFD database. It has become obvious that the same mechanisms used by ProSearch can be extended to Nucleic Acids. Ranier Fuchs has now allowed the extension of Prosearch Routines to search for Transcription Factor recognition sites. A forth coming extenstion will be other patterns like restriction enzyme sites, proteolysis sites, and others. In order to implement tfdsearch the file sites.dat from ncbi.nlm.nih.gov was required. Thes is the pattern file from David Ghosh's TFD database. I hope you all continue to use Prosearch with useful results. Future releases will only occur if there are new capablities added. cregex.c will allow you to update you regex files upon new database release without my intervention. -- Frank Kolakowski ======================================================================= |lfk@athena.mit.edu or lfk@eastman1.mit.edu or kolakowski@wccf.mit.edu| | Lee F. Kolakowski M.I.T. | | Dept of Chemistry Room 18-506 | | 77 Massachusetts Ave. Cambridge, MA 02139 | | AT&T: 1-617-253-1866 #include | ======================================================================= ||Desert Storm - Lasers have made this the cleanest *dirty war* ever.|| =======================================================================