Path: utzoo!utgpu!news-server.csri.toronto.edu!bonnie.concordia.ca!uunet!zaphod.mps.ohio-state.edu!usc!ucla-cs!news From: GERRI@IBM.COM (Gerri Oppedisano) Newsgroups: sci.med.aids Subject: AIDS drugs under pressure Message-ID: <1991Jan21.183652.21408@cs.ucla.edu> Date: 21 Jan 91 18:12:35 GMT Sender: news@cs.ucla.edu (Mr. News) Organization: UCLA, Computer Science Department Lines: 15 Approved: phil@wubios.wustl.edu Note: non-commercial reproduction. Nntp-Posting-Host: squid.cs.ucla.edu Archive-Number: 2918 >>I was wondering if any studies have been done in reguards to AZT/ddI/ddC >>and SCUBA diving. Some drugs respond differently when they are 'under >>pressure' and have new and sometimes dangerious side effects. >Why SCUBA? I wouldn't think of that as too much pressure. Now research >/c a hyperbaric oxygen chamber, I could understand. I would think the sort of questions one would need to answer are: are these drugs only stable within a certain range of pressure? If so, what is that range? ..Or is it fairly quick pressure changes that upset stability? How much of a change in pressure can mean bad things? What is the chance that bad things will happen? .. Then, what are the pressure levels or what is the change in pressure at certain depths when scuba diving? gerri@ibm.com