Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human beta-hexosaminidase beta-subunit (HEXB) gene, exon 2. Message-ID: Date: 25 Jan 91 13:00:53 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 46 Approved: lear@genbank.bio.net Checksum: 60283 3 LOCUS HUMHEXB02 399 bp ds-DNA PRI 25-JAN-1991 DEFINITION Human beta-hexosaminidase beta-subunit (HEXB) gene, exon 2. ACCESSION M23283 J03055 KEYWORDS beta-hexosaminidase; beta-hexosaminidase beta-subunit; lysosomal enzyme. SEGMENT 2 of 13 SOURCE Human DNA, clones pCosHex1, pCos[31.4,17.1] and lambda D2.3. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 399) AUTHORS Neote,K., Bapat,B., Dumbrille-Ross,A., Troxel,C., Schuster,S.M., Mahuran,D.J. and Gravel,R.A. TITLE Characterization of the human HEXB gene encoding lysosomal beta- hexosaminidase JOURNAL Genomics 3, 279-286 (1988) STANDARD full staff_review REFERENCE 2 (sites) AUTHORS Neote,K., Brown,C.A., Mahuran,D.J. and Gravel,R.A. TITLE Translation initiation in the HEXB gene encoding the beta-subunit of human beta-hexosaminidase JOURNAL J. Biol. Chem. 265, 20799-20806 (1990) STANDARD full staff_review COMMENT Draft entry and computer-readable sequence for [Genomics 3, 279-286 (1988)] kindly submitted by K.Neote, 19-AUG-1988. FEATURES Location/Qualifiers intron <1..112 /note="HEXB intron A" exon 113..258 /note="beta-hexosaminidase beta-subunit, exon 2 /nomgen='HEXB' /map='5q13' /hgml_locus_uid='LU0141W'" intron 259..>399 /note="HEXB intron B" BASE COUNT 118 a 81 c 72 g 128 t ORIGIN About 3.9 kb after segment 1. 1 ttacaatggg cagcatggat ttgaggagtt aactacaatg ttactagcac atctgtttta 61 aaaatttggc taaaatcctt ttaaaatgtg tttacattta tttctcaaac agatatcatg 121 gctatatttt tggtttctac aagtggcatc atgaacctgc tgaattccag gctaaaaccc 181 aggttcagca acttcttgtc tcaatcaccc ttcagtcaga gtgtgatgct ttccccaaca 241 tatcttcaga tgagtcttgt aagtacctat gcaatgtgag tgtattatat cccaggtgct 301 cgctgacgga cttaagtgcc aaaaactgac tccatgctag gaaccactga gttctcaacc 361 agtgagttta tgattcctat tttaaaaata accgggaaa //