Path: utzoo!utgpu!watserv1!watmath!uunet!bionet!lhc!ncifcrf!fcs260c2!toms
From: toms@fcs260c2.ncifcrf.gov (Tom Schneider)
Newsgroups: bionet.molbio.genbank
Subject: Re: Eukaryotic cis-acting transcription regulatory elements
Message-ID: <2040@fcs280s.ncifcrf.gov>
Date: 6 Feb 91 14:38:02 GMT
References: <9102051618.AA02080@replicon.lanl.gov>
Sender: news@ncifcrf.gov
Organization: NCI Supercomputer Facility, Frederick, MD
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In article <9102051618.AA02080@replicon.lanl.gov> jeh@REPLICON.LANL.GOV
(Jamie Hayden) writes:
>
>GenBank's policy has been to not store consensus sequences, but rather
>the sequences from which such consensus sequences were derived.  Times
>change, however, and we are currently evaluating the idea of creating
>such a division within the database, a subsection of promotors and other
>important, conserved regions.

GenBank already has the feature table, this would be completely sufficient to
satisfy everyone IF ONLY IT WERE KEPT UP TO DATE.  There are already hundreds
of binding sites of various kinds, but only certain kinds are recorded in the
database.  You don't need to go looking to create yet another feature of
GenBank, all you need to do is use what is there.

If you create consensus sequences you will be doing a huge disservice to
molecular biology by perpertrating this poor method.

>Jamie Hayden
>Annotator Coordinator
>GenBank

  Tom Schneider
  National Cancer Institute
  Laboratory of Mathematical Biology
  Frederick, Maryland  21702-1201
  toms@ncifcrf.gov