Path: utzoo!utgpu!watserv1!watmath!att!emory!wuarchive!uunet!av8tr!elliston
From: elliston@av8tr.UUCP (Keith Elliston)
Newsgroups: bionet.molbio.bio-matrix
Subject: Re: In defense of the Genome Boondoggle
Summary: nice C.V. Tom....
Message-ID: <632@av8tr.UUCP>
Date: 15 Feb 91 18:31:31 GMT
References: <12145@ur-cc.UUCP> <2050@fcs280s.ncifcrf.gov> <5714@husc6.harvard.edu> <2054@fcs280s.ncifcrf.gov>
Organization: Aviators Online BBS, Somerville, NJ
Lines: 141

In article <2054@fcs280s.ncifcrf.gov>, toms@fcs260c2.ncifcrf.gov (Tom Schneider) writes:

> And if you are going to poo-pa
> theoretical understanding, then I have some papers for you to read!  Start
> with:
> 
> author = "G. D. Stormo
>  and T. D. Schneider
>  and L. Gold
>  and A. Ehrenfeucht",
> title = "Use of the `Perceptron' algorithm to distinguish translational
> initiation sites in {E. coli.}",
> year = "1982",
> journal = "Nucl. Acids Res.",
> volume = "10",
> pages = "2997-3011"}
.
> author = "L. Gold
>  and D. Pribnow
>  and T. Schneider
>  and S. Shinedling
>  and B. S. Singer
>  and G. Stormo",
> title = "Translational initiation in prokaryotes.",
> year = "1981",
> journal = "Annu. Rev. Microbiol.",
> volume = "35",
> pages = "365-403"}
> 
> author = "G. D. Stormo
>  and T. D. Schneider
>  and L. M. Gold",
> title = "Characterization of translational initiation sites
> in {{E. coli.}}",
> year = "1982",
> journal = "Nucl. Acids Res.",
> volume = "10",
> pages = "2971-2996"}
> 
> author = "T. D. Schneider
>  and G. D. Stormo
>  and L. Gold
>  and A. Ehrenfeucht",
> title = "Information content of binding sites on nucleotide
> sequences",
> year = "1986",
> journal = "J. Mol. Biol.",
> volume = "188",
> pages = "415-431"}
.
> author = "T. D. Schneider
>  and G. D. Stormo",
> title = "Excess Information at Bacteriophage {T7} Genomic Promoters
> Detected by a Random Cloning Technique",
> year = "1989",
> journal = "Nucl. Acids Res.",
> volume = "17",
> pages = "659-674"}


Nice C.V. Tom....   

Not be pick nits or anything, but this discussion seems to be going over
board.  Perhaps it is time to drop the dueling keyboards for a moment, and
spend some time in the thought process.  I would dearly love to see a sort
of debate go on on this subject (genome sequencing), but would like to suggest
a more refined type of discussion.  Perhaps we could have an address by
the proponents of the genome sequence initiative, formulated collectively
by a group via e-mail.  We could then also have an address by a group
that is against the genome initiative, again collectively written by 
a group.  This might reduce the flaming, and bring us all to a more in-depth
understanding of the issues from both sides.  We could then discuss the
issues that are disparate and not have to be reduced to singular views
or flaming wars.

I suspect that a large number of the people reading these messages are like
me.... in that I see many advantages to genome sequencing, but also quite
a few shortcomings/disadvantes as well.

So... who wants to be the head of the Pro Genome sequencing group (Tom??)
How about the Anti Genome sequencing group? (Did I hear a woof.. or was
it a non-woof?)

Well....

Keith "where did Rob Harper go?" Elliston
elliston@msdrl.com

... inews fodder .....

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-- 
Keith O. Elliston          elliston@av8tr.UUCP           elliston@msdrl.com
AA5A N9734U                elliston@mbcl.rutgers.edu     elliston@biovax.bitnet

"Fly because you have to, to keep some semblance of sanity."