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From: BACKD@QUCDN.QueensU.CA
Newsgroups: comp.archives
Subject: [bionet.molbio.embldatabank...] Re: Eukaryotic cis-acting transcription regulatory elements
Message-ID: <1991Feb18.014545.13571@ox.com>
Date: 18 Feb 91 01:45:45 GMT
References: <91035.231138BACKD@QUCDN.QueensU.CA> <91037.235144BACKD@QUCDN.QueensU.CA>
Sender: emv@ox.com (Edward Vielmetti)
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Archive-name: bionet/molbio/tfd/1991-02-07
Archive-directory: ncbi.nlm.nih.gov:/repository/TFD/ [130.14.20.1]
Original-posting-by: BACKD@QUCDN.QueensU.CA
Original-subject: Re: Eukaryotic cis-acting transcription regulatory elements
Reposted-by: emv@ox.com (Edward Vielmetti)

Thanks to all of those who responded to my request.
This is a brief summary of my E-mail on the subject:

- David Gosh (Nucl. Acids Res. 18, 1749-1756) has developed a relational
 database of transcription factor recognition elements called TFD. The
 TFD database can be obtained in one of two ways:
   1. Anonymous FTP from NCBI.NLM.NIH.GOV in /repository/TFD
   2. From EMBL mailer. Send a message to the mailer as follows
      Address: NETSERVER@EMBL.BITNET
               HELP
               HELP TFD
               DIR TFD
     The mailer will return the appropriate help files to get you started.

- Dan Prestridge from Los Alamos Nat'l Labs writes that he has a program,
  SIGNAL SCAN available in MS-DOS or UNIX format that will scan a sequence
  file against the TFD database. The database is included on the disk.
  Mail Dan a request for either format at DXP%LIFE@LANL.GOV. The UNIX
  version can be E-mailed back, the MS-DOS version travels better on a
  diskette, so be prepared to send along two formatted discs.

- Those operating in the UNIX world have a third option.
  MBCRR.Harvard.Edu have a UNIX program called DYNAMIC that used the TFD
  database directly. D. Gosh refers to the program in his NAR paper.

 -Be aware the TFD database is about 500K.

 -Good luck and thanks for all the help.

Don Back, BACKD@QUCDN.QueensU.CA.BITNET
(613) 545-2982