Path: utzoo!utgpu!watserv1!watmath!uunet!spool.mu.edu!uwm.edu!bionet!lhc!lhc!hunter From: hunter@work.nlm.nih.gov (Larry Hunter) Newsgroups: bionet.molbio.bio-matrix Subject: Re: simulations Message-ID: Date: 1 Mar 91 19:45:41 GMT References: <9102281626.AA11878@genbank.bio.net> Sender: usenet@nlm.nih.gov (usenet news poster) Organization: National Library of Medicine Lines: 26 In-Reply-To: WILKISOND@medcolwi.bitnet's message of 28 Feb 91 16:30:00 GMT Douglas Wilison asks about neuronal simulation programs and techniques for the simulation of pharmcology of individual neurons. Doing detailed, realistic computer models of neurons (as would be needed for most inquiries in pharmacology) is technically and conceptually challenging. I suspect it will be difficult to find an adequate package that runs on a PC, but I do have a reference I would suggest: "Connectionist Modelling and Brain Function: The Developing Interface," ed. by S.J. Hanson and C.R. Olson, MIT Press 1990. This book contains both excellent review chapters and several specific models. I hope you find it helpful. Larry -- Lawrence Hunter, PhD. National Library of Medicine Bldg. 38A, MS-54 Bethesda. MD 20894 (301) 496-9300 (301) 496-0673 (fax) hunter@nlm.nih.gov (internet) hunter%nlm.nih.gov@nihcu (bitnet/earn)