Path: utzoo!utgpu!watserv1!watmath!uunet!spool.mu.edu!uwm.edu!bionet!root
From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human proto-oncogene vav, 5' end.
Message-ID: <Mar.6.05.01.39.1991.24741@genbank.bio.net>
Date: 6 Mar 91 13:01:42 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 62
Approved: lear@genbank.bio.net
Checksum: 60015     3

LOCUS       HUMVAVPO      680 bp ds-DNA             PRI       06-MAR-1991
DEFINITION  Human proto-oncogene vav, 5' end.
ACCESSION   M59834
KEYWORDS    proto-oncogene; transforming protein.
SOURCE      Human lymphocyte DNA, clone pSK 111.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 680)
  AUTHORS   Katzav,S., Cleveland,J.L., Heslop,H.E. and Pulido,D.
  TITLE     Loss of the aminoterminal helix-loop-helix domain of the vav
            proto-oncogene activates its transforming potential
  JOURNAL   Mol. Cell. Biol. (1990) In press
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     protein_bind    206..211
                     /note="AP1-like sequence."
                     /gene="proto-vav"
     protein_bind    236..242
                     /note="AP2-like sequence."
                     /gene="proto-vav"
     protein_bind    254..259
                     /note="Sp-1 binding site."
                     /gene="proto-vav"
     protein_bind    332..337
                     /note="Sp-1 binding site."
                     /gene="proto-vav"
     mRNA            409..680
                     /product="transforming protein vav"
                     /gene="proto-vav"
                     /partial
     mRNA            418..680
                     /product="transforming protein vav"
                     /gene="proto-vav"
                     /partial
     mRNA            418..680
                     /product="transforming protein vav"
                     /gene="proto-vav"
                     /partial
     protein_bind    441..446
                     /note="Sp-1 binding site."
                     /gene="proto-vav"
     CDS             498..680
                     /product="transforming protein vav"
                     /gene="proto-vav"
                     /codon_start=498
                     /partial
BASE COUNT      120 a    215 c    220 g    125 t
ORIGIN
        1 cggaagaaag agatgtagat tctgcatgga aggcgtgggg tggggctggg ctgcaggtgc
       61 tcagctcccc cccgccccat ggctcctcct cctccacccc ctctcagggc gacagttaca
      121 ggaaaggaat tctgggtata tttcagagtg tcactgccgc cgtctgcata tggaggaagc
      181 tcacccatct catagtctag ctggcctgac tcccccagcc ccccaactcc ccatgcccag
      241 gcctgtgtcg agtgggcgga agaaagagat gtagattctg catggaaggc gtggggtggg
      301 gctgggctgc aggtgctccc ccagctcccc cccgccccat ggctcctcct cctccacccc
      361 ctctcagggc gacagttaca ggaaagaaga ggaagtggta gcactagctg tcgctccaca
      421 ggcgagcagg gcaggcgtgc gggcgggtgg gtggtggagg ctgcgagggt gcacggccgg
      481 ccctgggcag ggtagccatg gagctgtggc gccaatgcac ccactggctc atccagtgcc
      541 gggtgctgcc gcccagccac cgcgtgacct gggatggggc tcaggtgtgt gaactggccc
      601 aggccctccg ggatggtgtc cttctgtgtc agctgcttaa caacctgcta ccccatgcca
      661 tcaacctgcg tgaggtcaac
//