Path: utzoo!utgpu!watserv1!watmath!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human T-cell lymphotropic virus type I (MT-1 cells), proviral 5' Message-ID: Date: 14 Mar 91 13:01:29 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 49 Approved: lear@genbank.bio.net Checksum: 35510 3 LOCUS HL1PRO1 805 bp ss-RNA VRL 14-MAR-1991 DEFINITION Human T-cell lymphotropic virus type I (MT-1 cells), proviral 5' LTR. ACCESSION J02030 KEYWORDS long terminal repeat; provirus; terminal repeat. SEGMENT 1 of 3 SOURCE HTLV1 proviral DNA from human cell line MT-1. ORGANISM Human T-cell lymphotropic virus type I Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Retroviridae; Oncovirinae; Type C oncovirus group; Mammalian type C oncoviruses. REFERENCE 1 (bases 1 to 805) AUTHORS Seiki,M., Hattori,S. and Yoshida,M. TITLE Human adult T-cell leukemia virus: Molecular cloning of the provirus DNA and the unique terminal structure JOURNAL Proc. Natl. Acad. Sci. U.S.A. 79, 6899-6902 (1982) STANDARD full staff_review REFERENCE 2 (sites) AUTHORS Ahmed,Y.F., Gilmartin,G.M., Hanly,S.M., Nevins,J.R. and Greene,W.C. TITLE The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation JOURNAL Cell 64, 727-737 (1991) STANDARD full staff_review COMMENT This proviral sequence contains a 755 bp long terminal repeat. Also reported is the 3' end of the viral RNA (see separate entry). The complete proviral sequence from human peripheral blood cells is also in a separate entry. FEATURES Location/Qualifiers LTR 21..774 /note="HTLV1 proviral 5' LTR" provirus 21..>805 /note="HTLV1 proviral DNA" BASE COUNT 167 a 271 c 195 g 172 t ORIGIN Near SmaI site. 1 catttaatca agggcattcc tgacaatgac catgagcccc aaatatcccc cgggggctta 61 gagcctccca gtgaaaaaca tttccgagaa acagaagtct gaaaaggtcg cggcccagac 121 taaggctctg acgtctcccc ccggagggca gctcagcacc ggctcaggct aggccctgac 181 gtgtccccct gaagacaaat cataagctca gacctccggg aagccaccgg gaaccaccca 241 tttcctcccc atgtttgtca agccgtcctc aggcgttgac gacaacccct cacctcaaaa 301 aacttttcat ggcacgcata tggctcaata aactaacagg agtctataaa agcgtggaga 361 cagttcagga gggggctcgc atctctcctt cacgcgcccg ccgccctacc tgaggccgcc 421 atccacgccg gttgagtcgc gttctgccgc ctcccgcctg tggtgcctcc tgaactgcgt 481 ccgccgtcta ggtaagttta gagctcaggt cgagaccggg cctttgtccg gcgctccctt 541 ggagcctacc tagactcagc cggctctcca cgctttgcct gaccctgctt gctcaactct 601 acgtctttgt ttcgttttct gttctgcgcc gttacagatc gaaagttcca cccctttccc 661 tttcattcac gactgactgc cggcttggcc cacggccaag taccggcgac tccgttggct 721 cggagccgcg acagcccatc ctatagcact ctcaggagag aaatttagta cacagttggg 781 ggctcgtccg ggatacgagc gcccc //