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From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
Message-ID: <Mar.27.05.05.11.1991.20243@genbank.bio.net>
Date: 27 Mar 91 13:05:11 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 44
Approved: lear@genbank.bio.net
Checksum: 09888     3

LOCUS       HUMIGHRFB     375 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62724
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-TS3.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..375
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..15
                     /gene="IgH"
                     /codon_start=1
                     /partial
     mat_peptide     16..375
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=16
                     /partial
BASE COUNT       91 a     96 c    103 g     85 t
ORIGIN      Chromosome 14.
        1 ataagtgccc actcccaggt gcagctggtg caatctgggt ctgagttgaa gaagcctggg
       61 gcctcagtga aggtttcctg caaggcttct ggatacacct tcactagcta tgctatgaat
      121 tgggtgcgac aggcccctgg acaagggctt gagtggatgg gatggatcaa caccaacact
      181 gggaacccaa cgtatgccca gggcttcaca ggacggtttg tcttctcctt ggacacctct
      241 gtcagcacgg catatctgca gatcagcagc ctaaaggctg acgacactgc cgtgtattac
      301 tgtgcgagag aagatagcaa tggctacaaa atatttgact actgggacca gggaaccctg
      361 gtcatcgtct cctca
//