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From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
Message-ID: <Mar.27.05.05.12.1991.20248@genbank.bio.net>
Date: 27 Mar 91 13:05:13 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 44
Approved: lear@genbank.bio.net
Checksum: 64271     3

LOCUS       HUMIGHRFC     447 bp ss-mRNA            PRI       27-MAR-1991
DEFINITION  Human IgH chain (monospecific rheumatoid factor) mRNA VDJ-region.
ACCESSION   M62726
KEYWORDS    V-region; diversity exon; immunoglobulin heavy chain; joining exon;
            monspecific rheumatoid factor.
SOURCE      Human synovial tissue Epstein-Barr transformed B cell, cDNA to
            mRNA, clone RF-SJ2.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 447)
  AUTHORS   Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J.
            and Capra,J.D.
  TITLE     The complete nucleotide sequences of the heavy chain variable
            regions of six monospecific rheumatoid factors derived from
            Epstein-Barr virus -transformed B cells isolated from the synovial
            tissue of patients with rheumatoid arthritis
  JOURNAL   J. Clin. Invest. 86, 1320-1328 (1990)
  STANDARD  full staff_entry
FEATURES             Location/Qualifiers
     CDS             1..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=1
                     /partial
     sig_peptide     1..60
                     /gene="IgH"
                     /codon_start=1
     mat_peptide     61..447
                     /product="immunoglobulin heavy chain"
                     /gene="IgH"
                     /codon_start=61
                     /partial
BASE COUNT       93 a    107 c    136 g    111 t
ORIGIN      Chromosome 14.
        1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgg tgtccagtgt
       61 caggtgcagc tggtggagtc tgggggaggc gtggtccagc ctgggaggtc cctgagactc
      121 tcctgtgcag cctctggatt caccttcagt agctatgcta tgcactgggt ccgccaggct
      181 ccaggcaagg ggctggagtg ggtggcagtt atatcatatg atggaagcaa taaatactac
      241 gcagactccg tgaagggccg attcaccatc tccagagaca attccaagaa cacgctgtct
      301 ctgcaaatga acagcctgag agctgaggac accgctgtgt attactgtgc gagaggccgg
      361 ttttgtagtg gtggtagctg ctactcttac tactactact actacatgga cgtctggggc
      421 aaagggacca cggtcaccgt ctcctca
//