Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!usc!apple!agate!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human IgH chain (monospecific rheumatoid factor) mRNA V-region. Message-ID: Date: 27 Mar 91 13:05:18 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 42 Approved: lear@genbank.bio.net Checksum: 04458 3 LOCUS HUMIGHRFG 351 bp ss-mRNA PRI 27-MAR-1991 DEFINITION Human IgH chain (monospecific rheumatoid factor) mRNA V-region. ACCESSION M62737 KEYWORDS V-region; immunoglobulin heavy chain; monspecific rheumatoid factor. SOURCE Human synovial tissue Epstein-Barr transformed B cell, cDNA to mRNA, clone GL-SJ2. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 351) AUTHORS Pascual,V., Randen,I., Thompson,K., Sioud,M., Forre,O., Natvig,J. and Capra,J.D. TITLE The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus -transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis JOURNAL J. Clin. Invest. 86, 1320-1328 (1990) STANDARD full staff_entry FEATURES Location/Qualifiers CDS 1..351 /product="immunoglobulin heavy chain" /gene="IgH" /codon_start=1 /partial sig_peptide 1..57 /gene="IgH" /codon_start=1 mat_peptide 58..351 /product="immunoglobulin heavy chain" /gene="IgH" /codon_start=58 /partial BASE COUNT 77 a 81 c 107 g 86 t ORIGIN Chromosome 14. 1 atggagtttg ggctgagctg ggttttcctc gttgctcttt taagaggtgt ccagtgtcag 61 gtgcagctgg tggactctgg gggaggcgtg gtccagcctg ggaggtccct gagactctcc 121 tgtgcagcct ctgcattcac cttcagtagc tatgctatgc actgggtccg ccaggctcca 181 ggcaaggggc tagagtgggt ggcagttata tcatatgatg gaagtaataa atactacgca 241 gactccgtga agggccgatt caccatctcc agagacaatt ccaagaacac gctgtatctg 301 caaatgaaca gcctgagagc tgaggacacg gctgtgtatt actgtgcgag a //