Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!zaphod.mps.ohio-state.edu!swrinde!elroy.jpl.nasa.gov!ucla-cs!usenet From: rjh1@midway.uchicago.edu (robert j hinde) Newsgroups: sci.med.aids Subject: seroconversion time and animal studies Message-ID: <1991May3.184320.23916@cs.ucla.edu> Date: 3 May 91 18:25:00 GMT Sender: news@midway.uchicago.edu (NewsMistress) Organization: University of Chicago -- Department of Chemistry Lines: 15 Approved: phil@wubios.wustl.edu Note: non-commercial reproduction. Nntp-Posting-Host: squid.cs.ucla.edu Archive-Number: 3124 The recent discussion of how long it takes to seroconvert after one is exposed to HIV made me wonder if any animal studies had been done on this subject. For example, one might inject SIV into a large number of monkeys and then see how long it takes each one to seroconvert. I know that these observations would not be directly transferable to humans because of differences between HIV and SIV and between monkeys and humans, but they still might provide some interesting information, if only about the spread of seroconversion times. So, my questions in a nutshell are: (1) Are such studies feasible, and if so, have they been done? (2) Is anything known about how informative such studies would be with respect to the seroconversion time question in humans?