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From: sjhg9320@uxa.cso.uiuc.edu (Maximum Slackness )
Newsgroups: bionet.molbio.proteins
Subject: Re: protein design using computational methods
Keywords: protein folding, computational methods, molecular dynamics
Message-ID: <1991May17.034252.24458@ux1.cso.uiuc.edu>
Date: 17 May 91 03:42:52 GMT
References: <719@mixcom.COM> <2158@fcs280s.ncifcrf.gov> <1991May17.005953.12252@beaver.cs.washington.edu>
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I'd kill to PostDoc in a protein lab where I could spend 50 hours a week
at the bench and 30 at a Computer. The people I am familiar with
that take a genetic approach are all Computer-innocent and the few
computationally oriented people I have discussed the problem with
are completely ignorant of the biology (e.g. Post-Translational Processing).

At any rate, there is no way predictive, general models can be made
until the biologists nail down considerably more of processing and assembly
pathways of proteins and get a better handle on how different cytosolic
proteins interact with each other and how membrane associated proteins
interact with their attendant lipids (once they determine local 
membrane assymetries for each individual protein.)
--

	No matter what you do, somebody always knew that you would...