Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!uwm.edu!spool.mu.edu!snorkelwacker.mit.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human Burkitt's lymphoma Ly91 mRNA for mu-immunoglobulin heavy Message-ID: Date: 19 May 91 12:00:36 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 56 Approved: lear@genbank.bio.net Checksum: 40079 3 LOCUS HUMIGLY91 260 bp ss-mRNA PRI 19-MAY-1991 DEFINITION Human Burkitt's lymphoma Ly91 mRNA for mu-immunoglobulin heavy chain with truncated VH region ACCESSION X52894 X13872 KEYWORDS immunoglobulin; immunoglobulin heavy chain; mu-immunoglobulin; rearranged DNA; variable region. SOURCE Homo sapiens RNA. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 260) AUTHORS Cogne,M., Mounir,S., Preud'homme,J.L., Nau,F. and Guglielmi,P. TITLE Burkitt's lymphoma cell lines producing truncated mu immunoglobulin heavy chains lacking part of the variable region JOURNAL Eur. J. Immunol. 18, 1485-1489 (1988) STANDARD full automatic REFERENCE 2 (bases 1 to 260; 1 to 260) AUTHORS Cogne,M.C. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 3 (bases 1 to 260) AUTHORS Sparkowski,J.J. and Das,A.K. TITLE The nucleotide sequence of greA, a suppressor gene that restores growth of an Escherichia coli RNA polymerase mutant at high temperature JOURNAL Nucleic Acids Res. 18, 6443-6443 (1990) STANDARD full automatic COMMENT *source: cell line=BL Ly91; cell type=B cell. From EMBL 26 entry HSIGLY91; dated 25-FEB-1991. FEATURES Location/Qualifiers CDS 55..>260 /note="Ly91 Ig mu heavy chain precursor (260 is 2nd base in codon)" /codon_start=55 CDS 55..111 /note="signal peptide (AA -19 to -1)" /codon_start=55 misc_feature 101..211 /note="VH exon derived region" CDS 112..>260 /note="mat. Ly91 Ig mu heavy chain (AA 1-50) (260 is 2nd base in codon)" /codon_start=112 misc_feature 154..156 /note="additional +14a codon" misc_feature 212..260 /note="mu CH1 exon 5' end derived region" BASE COUNT 52 a 71 c 66 g 71 t ORIGIN 1 cctgttccca ggagtttcca cttggtgatc agcactgaac acagaccacc aaccatggac 61 tttgggctta gctgggtttt ccttgttggt attttaaaag gtatgcaatg tgaggtgcaa 121 ctggtggaat ctgggggagg ctcgatacag ccaccagggc ggtcccagag accctcctat 181 acatgttctg gttccacttc tggtgatcat gggagtgcat ccgccccaac ccttttcccc 241 ctcgtctcct gtgagaattc //