Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!sdd.hp.com!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) Message-ID: Date: 22 May 91 12:17:57 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 53 Approved: lear@genbank.bio.net Checksum: 40371 3 LOCUS HPCVHCT18 963 bp ss-mRNA VRL 22-MAY-1991 DEFINITION Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) protein and E1-NS1/E2 protein junction, (isolate HCT18), partial cds. ACCESSION X53131 KEYWORDS E1 protein; NS1 protein; envelope protein; hepatitis; nonstructural protein. SOURCE Hepatitis C virus RNA. ORGANISM Hepatitis C virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Togaviridae incertae sedis. REFERENCE 1 (bases 1 to 963) AUTHORS Weiner,A.J. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 963) AUTHORS Weiner,A.J., Brauer,M.J., Rosenblatt,J., Richman,K.H., Tung,J., Crawford,K., Bonino,F., Saracco,G., Choo,Q.L., Houghton,M. and Han,J.H. TITLE Variable and hypervariable domains found in the regions of HCV corresponding to the flavivirius envelope and NS1 proteins and the pestivirus envelope glycoproteins JOURNAL Virology 180, 842-848 (1991) STANDARD full automatic COMMENT See X53131 to X53136 for the putative envelope sequence of other HCV isolates. From EMBL 26 entry HCVHCT18; dated 27-MAR-1991. FEATURES Location/Qualifiers CDS <1..>963 /note="putative envelope protein E1 and E1-NS1/E2 junction (321 AA)" /codon_start=1 BASE COUNT 175 a 297 c 275 g 216 t ORIGIN 1 cgcaatttgg gtaaggtcat cgataccctt acgtgcggct tcgccgacct catggggtat 61 ataccgctcg tcggcgcccc tcttggaggc gctgccaggg ccctggcgca tggcgtccgg 121 gttctggaag acggcgtgaa ctatgcaaca gggaaccttc ctggttgctc tttctctatc 181 ttccttctgg ccctgctctc ttgcctgact gtgcccgctt cagcccacca agtgcgcaac 241 tccacggggc tttaccatgt caccaatgat tgccccaact cgagtattgt atacgaagcg 301 gccgacgcca tcctgcacac tccggggtgt gtcccttgcg ttcacgaggg caacgtctcg 361 aggtgttggg tggcggtgac ccccacggtg gccaccaggg atggcaaact ccccacaacg 421 cagcttcgac gtcacatcga tctgcttgtc gggagcgcca ccctctgctc ggccctctat 481 gtgggggact tgtgcgggtc tgtctttctt gtcggccaac tgtttacctt ctctcccagg 541 cgccactgga cgacgcaagg ttgcaattgc tctatctatc ccggccacat aacggggcac 601 cgcatggcat gggatatgat gatgaactgg tcccctacgg cggcgttggt gatggctcag 661 ctgctccgga tcccacaagc catcatggac atgatcgctg gtgctcactg gggagtcctg 721 gcgggcatag cgtatttctc catggtgggg aactgggcga aggtcctggt agtgctgctg 781 ctatttgccg gcgtcgacgc ggaaacctac accagcgggg gaaatgccgg ccacaccatg 841 actgggattg ttaggttctt cgcgccaggc cccaaacaga acgtccattt gatcaacacc 901 aacggcagtt ggcacatcaa tagcacggcc ctgaactgca atgatagcct caacaccggc 961 tgg //