Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!sdd.hp.com!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) Message-ID: Date: 22 May 91 12:18:05 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 51 Approved: lear@genbank.bio.net Checksum: 44109 3 LOCUS HPCVHCT23 926 bp ss-mRNA VRL 22-MAY-1991 DEFINITION Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) protein and E1-NS1/E2 protein junction, (isolate HCT23), partial cds. ACCESSION X53132 KEYWORDS NS1 protein; envelope protein; hepatitis; nonstructural protein. SOURCE Hepatitis C virus RNA. ORGANISM Hepatitis C virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Togaviridae incertae sedis. REFERENCE 1 (bases 1 to 926) AUTHORS Weiner,A.J. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 926) AUTHORS Weiner,A.J., Brauer,M.J., Rosenblatt,J., Richman,K.H., Tung,J., Crawford,K., Bonino,F., Saracco,G., Choo,Q.L., Houghton,M. and Han,J.H. TITLE Variable and hypervariable domains found in the regions of HCV corresponding to the flavivirius envelope and NS1 proteins and the pestivirus envelope glycoproteins JOURNAL Virology 180, 842-848 (1991) STANDARD full automatic COMMENT See X53131 to X53136 for the putative envelope sequence of other HCV isolates. From EMBL 26 entry HCVHCT23; dated 27-MAR-1991. FEATURES Location/Qualifiers CDS <1..>926 /note="putative envelope protein E1 and E1-NS1/E2 junction (321 AA)" /codon_start=1 BASE COUNT 164 a 290 c 264 g 208 t ORIGIN 1 ggcttcgccg acctcatggg gtacataccg ctcgtcggcg cccctcttgg aggccgtgcc 61 agggccctgg cgcacggcgt ccgggttttg gaagacggcg tgaactatgc aacagggaac 121 cttcctggtt gctccttttc tatcttcctt ctggccctac tctcttgcct gaccgtgccc 181 gcttcagcct accaagtgcg caactctacg gggctttacc atgtcaccaa tgattgccct 241 aactcgagta ttgtgtacga ggcggccgat gccatcctgc acgctccggg gtgtgtccct 301 tgcgttcgcg aggataacgt ccgagatgtt gggtggcggt gacccccacg gtggccacca 361 aggacggcaa actccccaca acgcagcttc gacgtcacat cgatctgctt gtcgggagcg 421 ccaccctctg ctcggccctc tacgtggggg acctttgcgg gtccatcttt cttgtcggtc 481 aactgtttac cttctctccc aggcgccact ggacgacgca ggactgcaac tgttctatct 541 atcccggcca tataacgggt caccgcatgg catgggatat gatgatgaac tggtccccta 601 cggcggcatt ggtagtagct cagctgctcc ggatcccaca agccatcttg gacatgatcg 661 ctggtgctca ctggggagtc ctggcgggca tggcgtattt ctccatggtg gggaactggg 721 cgaaggtcct ggtagtgctg cttctatttg ccggcgtcga cgcggaaacc caccgtaccg 781 ggggaagtgc cgcccgcagc acggctggag ttgctagtct cttcacacca ggcgctaggc 841 agaacatcca gctgatcaac accaacggca gttggcacat caatagtacg gccttgaact 901 gcaatgacag ccttaccacc ggctgg //