Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) Message-ID: Date: 22 May 91 12:18:03 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 51 Approved: lear@genbank.bio.net Checksum: 61931 3 LOCUS HPCVHCT27 927 bp ss-mRNA VRL 22-MAY-1991 DEFINITION Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) protein and E1-NS1/E2 protein junction (isolate HCT27), partial cds. ACCESSION X53133 KEYWORDS NS1 protein; envelope protein; hepatitis; nonstructural protein. SOURCE Hepatitis C virus RNA. ORGANISM Hepatitis C virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Togaviridae incertae sedis. REFERENCE 1 (bases 1 to 927) AUTHORS Weiner,A.J. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 927) AUTHORS Weiner,A.J., Brauer,M.J., Rosenblatt,J., Richman,K.H., Tung,J., Crawford,K., Bonino,F., Saracco,G., Choo,Q.L., Houghton,M. and Han,J.H. TITLE Variable and hypervariable domains found in the regions of HCV corresponding to the flavivirius envelope and NS1 proteins and the pestivirus envelope glycoproteins JOURNAL Virology 180, 842-848 (1991) STANDARD full automatic COMMENT See X53131 to X53136 for the putative envelope sequence of other HCV isolates. From EMBL 26 entry HCVHCT27; dated 27-MAR-1991. FEATURES Location/Qualifiers CDS <1..>927 /note="putative envelope protein E1 and E1-NS1/E2 junction" /codon_start=1 BASE COUNT 166 a 287 c 261 g 213 t ORIGIN 1 ggcttcgccg acctcatggg gtacattccg ctcgtcggcg ctcctcttgg gggcgctgcc 61 agggccctgg cgcatggcgt ccgggttctg gaagacggcg tgaactatgc aacagggaac 121 cttcctggtt gctctttctc tatcttcctt ctggctctgc tctcttgcct gaccgtgccc 181 gcatcggcct accaagtacg caactcctcg ggcatttacc atgtcaccaa tgattgccct 241 aattcgagta ttgtgtacga gacggccgac accatcctac actctccggg gtgtgtccct 301 tgcgttcgcg agggtaacgc ctcgaaatgt tgggtgccgg tagcccccac agtggccacc 361 agggacggca acctccccgc aacgcagctt cgacgtcaca tcgatctgct tgtcgggagt 421 gccacccttt gctcggccct ctatgtgggg gacttgtgcg ggtctgtctt tcttgtcggt 481 caactgttca ctttctcccc caggcgccac tggacaacgc aagattgcaa ctgctctatc 541 taccccggcc atataacggg acaccgcatg gcatgggata tgatgatgaa ctggtcccct 601 acagcagcgc tggtaatggc tcagctgctc aggatcccgc aagccatctt ggacatgatc 661 gctggtgctc actggggagt cctagcgggc atagcgtatt tctccatggt ggggaactgg 721 gcgaaggtcc tggtggtgct gttgctgttt gccggcgtcg atgcgacaac ctataccacc 781 ggggggaatg ctgccaggac cacgcaggcg ctcaccagtt ttttcagccc aggcgccaag 841 caggatatcc agctgatcaa caccaacggc agttggcaca tcaatcgcac ggccttgaac 901 tgtaatgcga gcctcgacac tggctgg //