Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) Message-ID: Date: 22 May 91 12:18:01 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 51 Approved: lear@genbank.bio.net Checksum: 11477 3 LOCUS HPCVTH 963 bp ss-mRNA VRL 22-MAY-1991 DEFINITION Hepatitis C virus (HCV) genomic RNA for a putative envelope (E1) protein and E1-NS1/E2 protein junction (isolate Th), partial cds. ACCESSION X53134 KEYWORDS NS1 protein; envelope protein; hepatitis; nonstructural protein. SOURCE Hepatitis C virus RNA. ORGANISM Hepatitis C virus Viridae; ss-RNA enveloped viruses; Positive strand RNA virus; Togaviridae incertae sedis. REFERENCE 1 (bases 1 to 963) AUTHORS Weiner,A.J. JOURNAL Unpublished (1990) STANDARD full automatic REFERENCE 2 (bases 1 to 963) AUTHORS Weiner,A.J., Brauer,M.J., Rosenblatt,J., Richman,K.H., Tung,J., Crawford,K., Bonino,F., Saracco,G., Choo,Q.L., Houghton,M. and Han,J.H. TITLE Variable and hypervariable domains found in the regions of HCV corresponding to the flavivirius envelope and NS1 proteins and the pestivirus envelope glycoproteins JOURNAL Virology 180, 842-848 (1991) STANDARD full automatic COMMENT See X53131 to X53136 for the putative envelope sequence of other HCV isolates. From EMBL 26 entry HCVTH; dated 27-MAR-1991. FEATURES Location/Qualifiers CDS <1..>963 /note="putative envelope protein E1 and E1-NS1/E2 junction" /codon_start=1 BASE COUNT 169 a 301 c 279 g 214 t ORIGIN 1 cgcaatttgg gtaaggtcat cgataccctt acgtgcggct tcgccgacct catggggtac 61 ataccgctcg tcggcgcccc tcttgggggc gctgccaggg ccctggcgca tggcgtccgg 121 gttctggaag acggcgtgaa ctatgcaaca gggaaccttc ctggttgctc tttctctctc 181 ttccttctgg ccctgctctc ttgtctgacc gtgcccgctt cagcctacca agtgcgcaac 241 tccacggggc tttaccatgt caccaacgat tgccccaact cgagtattgt gtacgaggcg 301 gccgatgcta tcctgcacgc tccggggtgt gtcccttgcg ttcgcgaggg taacgcctcg 361 aggtgttggg tggcgatgac ccccacggtg gccaccaggg acggcagact ccccacaacg 421 cagctgcgac gtcacatcga tctgcttgtc gggagcgcca ccctctgctc ggccctctac 481 gtgggggacc tgtgcgggtc catctttctt gtcggtcaac tgttcacctt ctctcccagg 541 cgccactgga cgacgcaagg ttgcaattgc tctatctatc ccggccatat aacgggtcac 601 cgcatggcat gggatatgat gatgaactgg tcccctacga cggcgttggt agtagctcag 661 ctgctccgga tcccacaagc catcttggac atgatcgctg gtgctcactg gggagtcctg 721 gcgggcatag cgtatttctc catggtgggg aactgggcaa aggtcctggt agtgctgctg 781 ctatttgccg gcgtcgacgc ggaaaccacc gtcaccgggg gaagtgccgc ccatggcgcg 841 cttggaattg ctagtctctt caaccagggc gccaggcaga acatccagct gatcaacacc 901 aacggcagtt ggcacatcaa tagcacggcc ttgaactgca atgatagcct caacaccggc 961 tgg //