Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!zaphod.mps.ohio-state.edu!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, Message-ID: Date: 23 May 91 12:00:55 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 42 Approved: lear@genbank.bio.net Checksum: 36142 3 LOCUS HUMTCBVB 399 bp ss-mRNA PRI 23-MAY-1991 DEFINITION Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, clone ph5. ACCESSION M14260 KEYWORDS T-cell antigen receptor; diversity region; joining region; variable region. SOURCE Human tonsil, cDNA to mRNA, clone ph5. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 399) AUTHORS Tillinghast,J.P., Behlke,M.A. and Loh,D.Y. TITLE Structure and diversity of the human T-cell receptor beta-chain variable region genes JOURNAL Science 233, 879-883 (1986) STANDARD simple staff_review COMMENT V-D boundary not clearly indicated in [1]. FEATURES Location/Qualifiers CDS 1..>399 /partial /note="T-cell receptor V-region (V-D-J) /nomgen='TCRB' /map='7q32 or 7q35' /hgml_locus_uid='LP0151Q'" /codon_start=1 sig_peptide 1..57 /note="T-cell receptor signal peptide" /codon_start=1 mat_peptide 58..>399 /partial /note="T-cell receptor V-region (V-D-J)" /codon_start=58 misc_recomb 357^358 /note="D-region end/J-region start" BASE COUNT 89 a 110 c 114 g 86 t ORIGIN Chromosome 7q32 or 7q35. 1 atgggcacca ggctcctctg ctgggtggtc ctgggtttcc tagggacaga tcacacaggt 61 gctggagtct cccagtcccc taggtacaaa gtcgcaaaga gaggacagga tgtagctctc 121 aggtgtgatc caatttcggg tcatgtatcc cttttttggt accaacaggc cctggggcag 181 gggccagagt ttctgactta tttccagaat gaagctcaac tagacaaatc ggggctgccc 241 agtgatcgct tctttgcaga aaggcctgag ggatccgtct ccactctgaa gatccagcgc 301 acacagcagg aggactccgc cgtgtatctc tgtgccagca gaccaaacca tgggtcgtac 361 gagcagtact tcgggccggg caccaggctc acggtcaca //