Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!zaphod.mps.ohio-state.edu!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, Message-ID: Date: 23 May 91 12:00:56 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 42 Approved: lear@genbank.bio.net Checksum: 05835 3 LOCUS HUMTCBVC 396 bp ss-mRNA PRI 23-MAY-1991 DEFINITION Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, clone 22. ACCESSION M14261 KEYWORDS T-cell antigen receptor; diversity region; joining region; variable region. SOURCE Human tonsil, cDNA to mRNA, clone ph22. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 396) AUTHORS Tillinghast,J.P., Behlke,M.A. and Loh,D.Y. TITLE Structure and diversity of the human T-cell receptor beta-chain variable region genes JOURNAL Science 233, 879-883 (1986) STANDARD simple staff_review COMMENT V-D boundary not clearly indicated in [1]. FEATURES Location/Qualifiers CDS 1..>396 /partial /note="T-cell receptor V-region (V-D-J) /nomgen='TCRB' /map='7q32 or 7q35' /hgml_locus_uid='LP0151Q'" /codon_start=1 sig_peptide 1..57 /note="T-cell receptor signal peptide" /codon_start=1 mat_peptide 58..>396 /partial /note="T-cell receptor V-region (V-D-J)" /codon_start=58 misc_recomb 348^349 /note="D-region end/J-region start" BASE COUNT 99 a 102 c 104 g 91 t ORIGIN Chromosome 7q32 or 7q35. 1 atggggacca gcctcctctg ctggatggcc ctctgtctcc tgggggcaga tcaggagata 61 tctggagtct cccacaaccc cagacacaag atcacaaaga ggggacagaa tgtaactttc 121 aggtgtgatc caatttctga acacaaccgc ctttattggt accgacagaa ccctgggcag 181 ggcccagagt ttctgactta cttccagaat gaagctcaac tggaaaaatc agggctgctc 241 agtgatcgga tctctgcaga gaggcctaag ggatctttct ccaccttgga gatccagcgc 301 acagagcagg gggactcggc catgtatctc tgtgccagca gctctttctc tggaaacacc 361 atatattttg gagagggaag ttggctcact gttgta //