Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!zaphod.mps.ohio-state.edu!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, Message-ID: Date: 23 May 91 12:01:02 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 42 Approved: lear@genbank.bio.net Checksum: 14766 3 LOCUS HUMTCBVF 402 bp ss-mRNA PRI 23-MAY-1991 DEFINITION Human T-cell receptor rearranged beta-chain V-region (V-D-J) mRNA, clone ph8. ACCESSION M14264 KEYWORDS T-cell antigen receptor; diversity region; joining region; variable region. SOURCE Human tonsil, cDNA to mRNA, clone ph8. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 402) AUTHORS Tillinghast,J.P., Behlke,M.A. and Loh,D.Y. TITLE Structure and diversity of the human T-cell receptor beta-chain variable region genes JOURNAL Science 233, 879-883 (1986) STANDARD simple staff_review COMMENT V-D boundary not clearly indicated in [1]. FEATURES Location/Qualifiers CDS 1..>402 /partial /note="T-cell receptor V-region (V-D-J) /nomgen='TCRB' /map='7q32 or 7q35' /hgml_locus_uid='LP0151Q'" /codon_start=1 sig_peptide 1..57 /note="T-cell receptor signal peptide" /codon_start=1 mat_peptide 58..>402 /partial /note="T-cell receptor V-region (V-D-J)" /codon_start=58 misc_recomb 351^352 /note="D-region end/J-region start" BASE COUNT 93 a 106 c 107 g 96 t ORIGIN Chromosome 7q32 or 7q35. 1 atgggctcct ggaccctctg ctgtgtgtcc ctttgcatct tggtagcaaa gcacacagat 61 gctggagtta tccagtcacc ccggcacgag gtgacagaga tgggacaaga agtgactctg 121 agatgtaaac caatttcagg acatgactac cttttctggt acagacagac catgatgcgg 181 ggactggagt tgctcattta ctttaacaac aacgttccga tagatgattc agggatgccc 241 gaggatcgat tctcagctaa gatgcctaat gcatcattct ccactctgag gatccagccc 301 tcagaaccca gggactcagc tgtgtacttc tgtgccagca gtttagcgcc gtctggggcc 361 aacgtcctga ctttcggggc cggcagcagg ctgaccgtgc tg //