Path: utzoo!utgpu!news-server.csri.toronto.edu!rpi!zaphod.mps.ohio-state.edu!wuarchive!uunet!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Human T-cell receptor rearranged beta-chain V-region (V-D-J), mRNA, Message-ID: Date: 23 May 91 12:01:05 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 42 Approved: lear@genbank.bio.net Checksum: 51881 3 LOCUS HUMTCBVG 396 bp ss-mRNA PRI 23-MAY-1991 DEFINITION Human T-cell receptor rearranged beta-chain V-region (V-D-J), mRNA, clone ph11. ACCESSION M14265 KEYWORDS T-cell antigen receptor; diversity region; joining region; variable region. SOURCE Human tonsil, cDNA to mRNA, clone ph11. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 1 to 396) AUTHORS Tillinghast,J.P., Behlke,M.A. and Loh,D.Y. TITLE Structure and diversity of the human T-cell receptor beta-chain variable region genes JOURNAL Science 233, 879-883 (1986) STANDARD simple staff_review COMMENT V-D boundary not clearly indicated in [1]. FEATURES Location/Qualifiers CDS 1..>396 /partial /note="T-cell receptor V-region (V-D-J) /nomgen='TCRB' /map='7q32 or 7q35' /hgml_locus_uid='LP0151Q'" /codon_start=1 sig_peptide 1..57 /note="T-cell receptor signal peptide" /codon_start=1 mat_peptide 58..>396 /partial /note="T-cell receptor V-region (V-D-J)" /codon_start=58 misc_recomb 354^355 /note="D-region end/J-region start" BASE COUNT 101 a 100 c 97 g 98 t ORIGIN Chromosome 7q32 or 7q35. 1 atggactcct ggaccttctg ctgtgtgtcc ctttgcatct tggtagcgaa gcatacagac 61 gctggagtta tccagtcacc ccgccatgag gtgacagaga tgggacaaga agtgactctg 121 agatgtaaac caatttcagg ccacaactcc cttttctggt acagacagac catgatgcgg 181 ggactggagt tgctcattta ctttaacaac aacgttccga tagatgattc agggatgccc 241 gaggatcgat tctcagctaa gatgcctaat gcatcattct ccactctgaa gatccagccc 301 tcagaaccca gggactcagc tgtgtacttc tgtgccagca gtttaagggc gggaactgaa 361 gctttctttg gacaaggcac cagactcaca gttgta //