Path: utzoo!utgpu!watserv1!watmath!att!emory!ox.com!caen!zaphod.mps.ohio-state.edu!wuarchive!uunet!stanford.edu!agate!bionet!root
From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse (GAT-specific) subgroup II germline Ig V(H)2b-3 gene related
Message-ID: <May.27.05.43.02.1991.26831@genbank.bio.net>
Date: 27 May 91 12:43:02 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 60
Approved: lear@genbank.bio.net
Checksum: 13474     3

LOCUS       MUSIGVH2B     628 bp ds-DNA             ROD       27-MAY-1991
DEFINITION  Mouse (GAT-specific) subgroup II germline Ig V(H)2b-3 gene related
            to anti-GAT Ab1 sequences
ACCESSION   X03573
KEYWORDS    germline; immunoglobulin; immunoglobulin heavy chain;
            immunoglobulin heavy chain subgroup VH-II; signal peptide;
            variable region.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 628)
  AUTHORS   Schiff,C., Milili,M., Hue,I., Rudikoff,S. and Fougereau,M.
  TITLE     Genetic basis for expression of the idiotypic network: One unique
            Ig VH germline gene accounts for the major family of Ab1 and Ab3
            (Ab1') antibodies of the GAT system
  JOURNAL   J. Exp. Med. 163, 573-587 (1986)
  STANDARD  full automatic
COMMENT     EPD; 14072; Mm Ig VH4b-3.
            
            See also <X03571> and <X03572>
            
            From EMBL    entry MMIGVH2B;  dated 16-JAN-1991.
FEATURES             Location/Qualifiers
     sig_peptide     join(144..189,269..279)
     mRNA            <190..189
                     /note="exon 1"
     CDS             join(144..189,269..573)
                     /product="H2b-3 coding region"
                     /codon_start=144
     misc_signal     43..52
                     /note="conserved element; pot. cell type specific
                     transcription control"
     promoter        66..73
                     /note="pot. TATA-box"
     intron          190..268
                     /note="intron I"
     mRNA            269..573
     mRNA            269..573
                     /note="exon 2"
     mat_peptide     280..573
                     /product="H2b-3 coding region"
     misc_feature    574..580
                     /note="7 bp recombination signal"
     misc_feature    604..612
                     /note="9 bp recombination signal"
BASE COUNT      177 a    151 c    147 g    153 t
ORIGIN
        1 agctagaaca tccttatgta agaaagatcc tgccacatga atatgcaaat catgagtctg
       61 tgattataaa tacgtgcata tccacaccaa acaacatatg aacactgttt tctctacagt
      121 cactgaatct caaggtcctt acaatgaaat gcagctgggt catcttcttc ctgatggcag
      181 tggttatagg taaggggctc ccaagtccca aacttgaggg gccacacact ctgtgacagt
      241 ggcaatcact ttgtctttct ttctacagga atcaattcag aggttcagct gcagcagtct
      301 ggggcagagc ttgtgaggtc aggggcctca gtcaagttgt cctgcacagc ttctggcttc
      361 aacattaaag actactatat gcactgggtg aagcagaggc ctgaacaggg cctggagtgg
      421 attggatgga ttgatcctga gaatggtgat actgaatatg ccccgaagtt ccagggcaag
      481 gccactatga ctgcagacac atcctccaac acagcctacc tgcagctcag cagcctgaca
      541 tctgaggaca ctgccgtcta ttactgtaat gcacacagtg ttgcaaccac atcctgagag
      601 tgtcagaaac cataaagtgc aggaagct
//