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From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Mouse (GAT-specific) subgroup II germline Ig V(H)4a-3 gene related
Message-ID: <May.27.05.43.03.1991.26839@genbank.bio.net>
Date: 27 May 91 12:43:03 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 66
Approved: lear@genbank.bio.net
Checksum: 57988     4

LOCUS       MUSIGVH4A    1009 bp ds-DNA             ROD       27-MAY-1991
DEFINITION  Mouse (GAT-specific) subgroup II germline Ig V(H)4a-3 gene related
            to anti-GAT Ab1 sequences
ACCESSION   X03572
KEYWORDS    germline; immunoglobulin; immunoglobulin heavy chain;
            immunoglobulin heavy chain subgroup VH-II; signal peptide;
            variable region.
SOURCE      Mus musculus DNA.
  ORGANISM  Mus musculus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Schiff,C., Milili,M., Hue,I., Rudikoff,S. and Fougereau,M.
  TITLE     Genetic basis for expression of the idiotypic network: One unique
            Ig VH germline gene accounts for the major family of Ab1 and Ab3
            (Ab1') antibodies of the GAT system
  JOURNAL   J. Exp. Med. 163, 573-587 (1986)
  STANDARD  full automatic
COMMENT     EPD; 14071; Mm Ig VH4a-3.
            
            See also <X03571> and <X03573>
            
            From EMBL    entry MMIGVH4A;  dated 16-JAN-1991.
FEATURES             Location/Qualifiers
     sig_peptide     join(431..476,556..566)
     mRNA            <477..476
                     /note="exon 1"
     CDS             join(431..476,556..860)
                     /product="H4a-3 coding region"
                     /codon_start=431
     misc_signal     331..339
                     /note="conserved element; pot. cell type specific
                     transcription control"
     promoter        353..360
                     /note="pot. TATA-box"
     intron          477..555
                     /note="intron I"
     mRNA            556..860
     mRNA            556..860
                     /note="exon 2"
     mat_peptide     567..860
                     /product="H4a-3 coding region"
     misc_feature    861..867
                     /note="7 bp recombination signal"
     misc_feature    891..899
                     /note="9 bp recombination signal"
BASE COUNT      289 a    222 c    217 g    281 t
ORIGIN
        1 ggccactatt aatttcaagt gtatgaaaaa agattgcaaa ttctcataaa tatgttttta
       61 aagttccagt aaccattttc tctcattgct tctaacacca ataaatttgt caccaagtaa
      121 agtgagtgtc tcaggttagg attctatttt tgaaaaatga aagattaggc ttgatattgt
      181 atctaagtgg tctgcacatg tctcagggaa agttcctaag acagaattag gatttggtcc
      241 ccagcatcct gttgactgac ccaggtgcac tcaacttcct tcttctccag ccagaatgtt
      301 cttatgtaag aaagatcctg cctcatgaat atgcaaacat gagtctgtga ttataaatac
      361 agagatatcc ataccaaaca acttatgagc actgttttct ctacagtcac tgaatctcaa
      421 ggtccttaca atgaaatgca gctgggtcat cttcttcctg atggcagtgg ttacaggtaa
      481 ggagctccca agtcccaaac ttgaggggcc atacactctg tgacagtggc agtcactttg
      541 cctttctttc tacaggggtc aattcagagg ttcagctgca gcagtctggg gctgagcttg
      601 tgaggccagg ggccttagtc aagttgtcct gcaaagcttc tggcttcaac attaaagact
      661 actatatgca ctgggtgaag cagaggcctg aacagggcct ggagtggatt ggatggattg
      721 atcctgagaa tggtaatact atatatgacc cgaagttcca gggcaaggcc agtataacag
      781 cagacacatc ctccaacaca gcctacctgc agctcagcag cctgacatct gaggacactg
      841 ccgtctatta ctgtgctaga cacagtgttg caaccacatc ctgagtgtgt cagaaaccat
      901 agaaccgcag gaagctgcct gagactgaga tgacagacaa tattatcctg aagattttct
      961 cagaaatagc cattttgtga gcctgcctat ctacagtttt aaatgctat
//