Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Mouse germline immunoglobulin V(H)II gene H13-3 Message-ID: Date: 27 May 91 12:43:08 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 49 Approved: lear@genbank.bio.net Checksum: 02639 3 LOCUS MUSIGVH6 469 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II gene H13-3 ACCESSION X02459 KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 469) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH6; dated 02-JUL-1986. FEATURES Location/Qualifiers mRNA <1..6 /note="exon 1 fragment" CDS 1..6 /note="signal peptide fragment (aa -6 to -5) (1 is 2nd base in codon) (6 is 1st base in codon)" /codon_start=1 intron 7..89 /note="intron I" mRNA 90..>89 /note="exon 2" CDS 90..100 /note="signal peptide fragment (aa -4 to -1) (90 is 2nd base in codon)" /codon_start=90 CDS 101..394 /note="H13-3 variable region (aa 1-94, kabat numbering)" /codon_start=101 misc_feature 395..401 /note="rearrangement signal" misc_feature 425..433 /note="rearrangement signal" BASE COUNT 137 a 118 c 116 g 98 t ORIGIN 1 ctgcaggtaa ggggatcacc agttcaaaat ctgaagagga aacagaatct gaggtaacag 61 tgatacctac tatgcctttc tgtccacagg tgtccactcc caggtccagc tgcagcagtc 121 tgcagctgaa ctggcaagac ctggggcctc agtgaagatg tcctgcaagg cttctggcta 181 cacctttact agctacacga tgcactgggt aaaacagagg cctggacagg gtctggaatg 241 gattggatac attaatccta gcagtggata tactgagtac aatcagaagt tcaaggacaa 301 gaccacattg actgcagaca aatcctccag cacagcctac atgcaactga gcagcctgac 361 atctgaggac tctgcggtct attactgtgc aagacacagt ggtgcaacca catcccgact 421 gtgtcagaaa ccctagcaga acaggaagct tacctgggac tgagaattc //