Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!root From: GenBank-Updates@genbank.bio.net Newsgroups: bionet.molbio.genbank.updates Subject: Mouse germline immunoglobulin V(H)II gene H16 Message-ID: Date: 27 May 91 12:43:13 GMT Sender: root@genbank.bio.net Distribution: bionet Lines: 45 Approved: lear@genbank.bio.net Checksum: 26312 3 LOCUS MUSIGVH8 377 bp ds-DNA ROD 27-MAY-1991 DEFINITION Mouse germline immunoglobulin V(H)II gene H16 ACCESSION X02461 KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain; signal peptide; variable region; variable region subgroup VH-II. SOURCE Mus musculus DNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 377) AUTHORS Schiff,C., Milili,M. and Fougereau,M. TITLE Functional and pseudogenes are similarly organized and may equally contribute to the extensive antibody diversity of the IgVHII family JOURNAL EMBO J. 4, 1225-1230 (1985) STANDARD full automatic COMMENT From EMBL entry MMIGVH8; dated 02-JUL-1986. FEATURES Location/Qualifiers mRNA <1..6 /note="exon 1 fragment" CDS 1..6 /note="pot. signal peptide (aa -6 to -5) (1 is 2nd base in codon) (6 is 1st base in codon)" /codon_start=1 intron 7..89 /note="intron I" mRNA 90..>89 /note="H16 mRNA; exon 2" CDS 90..100 /note="pot. signal peptide (aa -4 to -1) (90 is 2nd base in codon)" /codon_start=90 CDS 101..377 /note="H16 variable region (aa 1-88/kabat numbering) (377 is 1st base in codon)" /codon_start=101 BASE COUNT 101 a 96 c 92 g 88 t ORIGIN 1 ctgcaggtaa ggggctcacc atttccaaat ctgaagaaaa gaaatggctt gtgatgtcac 61 tgacatccac tctgtctttc tctcctcagg cgtccactct gaggtccagc ttcagcagtc 121 aggacctgag ctggtgaaac ctggggcctc agtgaagata tcctgcaagg cttctggata 181 cacattcact gactacaaca tgcactgggt gaagcagagc catggaaaga gccttgagtg 241 gattggatat atttatcctt acaatggtgg tactggctac aaccagaagt tcaagagcaa 301 ggccacattg actgtagaca attcctccag cacagcctac atggacgtcc gcagcctgac 361 atctgaggac tctgcag //