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From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Rat gene for growth hormone (presomatotropin).
Message-ID: <May.28.11.49.24.1991.9925@genbank.bio.net>
Date: 28 May 91 18:49:25 GMT
Sender: will@genbank.bio.net
Distribution: bionet
Lines: 92
Approved: lear@genbank.bio.net
Checksum: 36539     5

LOCUS       RATGROW2     2243 bp ds-DNA             ROD       2
DEFINITION  Rat gene for growth hormone (presomatotropin).
ACCESSION   V01238
KEYWORDS    germline; growth hormone; signal peptide.
SOURCE      Rattus norvegicus DNA.
  ORGANISM  Rattus norvegicus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE   1  (bases 1 to 2243)
  AUTHORS   Page,G.S., Smith,S. and Goodman,H.M.
  TITLE     DNA sequence of the rat growth hormone gene: location of the 5'
            terminus of the growth hormone mRNA and identification of an
            internal transposon-like element
  JOURNAL   Nucleic Acids Res. 9, 2087-2104 (1981)
  STANDARD  full automatic
COMMENT     This entry was previously named <RNGROWZ1>.
            
            See also entries <RNGROW1> and <RNGROW3>.
            
            Two 200bp direct repeats are flanked by two 15bp direct repeats in
            IVS 2.
            
            From EMBL    entry RNGROW2;  dated 06-JUL-1989.
FEATURES             Location/Qualifiers
     precursor_RNA   230..2210
                     /note="presomatotropin"
     CDS             290..299
                     /note="reading frame (299 is 1st base in codon)"
                     /codon_start=290
     intron          300..484
                     /note="ivs 1"
     CDS             485..645
                     /note="reading frame (485 is 2nd base in codon)"
                     /codon_start=485
     intron          646..1259
                     /note="ivs 2"
     CDS             1260..1376
                     /note="reading frame"
                     /codon_start=1260
     intron          1377..1534
                     /note="ivs 3"
     CDS             1535..1696
                     /note="reading frame"
                     /codon_start=1535
     intron          1697..1908
                     /note="ivs 4"
     CDS             1909..2106
                     /note="reading frame"
                     /codon_start=1909
     polyA_site      2210..2210
                     /note="poly A addition site"
BASE COUNT      553 a    605 c    573 g    512 t
ORIGIN
        1 cgtaccattg cccataaact tggcaaaggc ggcggtggaa aggtaagatc agggacgtga
       61 ccgcaggaga gcagtgggga cgcgatgtgt gggaggagct tctaaattat ccatcagcac
      121 aagctgtcag tggctccagc catgaataaa tgtataggga aaaaggcagg agccttgggg
      181 tcgaggaaaa caggtagggt ataaaaaggg catgcaaggg accaaatcca gcaccctcga
      241 gcccagattc caaactactc aggtcctgtg gacagatcac tgagtggcga tggctgcagg
      301 taagcatgcg cagatcccgc tgggtgtggt ttggaccaaa gagccttgaa gatggatctg
      361 aggcttctag tgtgagggca tcccaacttc cgcccatgtt gggaacattc tgggacccta
      421 tggggattgg gagagattgg tccttgctcc cagcctcctc ctgtcctcct gtctctcttt
      481 ctagactctc agactccctg gctcctgacc ttcagcctgc tctgcctgct gtggcctcaa
      541 gaggctggtg ctttccctgc catgcccttg tccagtctgt ttgccaatgc tgtgctccga
      601 gcccagcacc tgcaccagct ggctgctgac acctacaaag agttcgtaag ttcctcggtg
      661 ttgggtgcct gactgtggaa gcaggaaagg ggcacgatcc caccctcgcc ccgaatccct
      721 gcccccagga agtcatagga ggaaactatg ccgttagatg agcagaaaaa gaatgggtcg
      781 tccataagca gtaatgacag agagggctgg agagatggct cagtggttaa gagcacccga
      841 ctgctcttcc aaaggtcctg agttcaattc ccagcaacca catggtggct cacaaccatc
      901 tgtaaagaga tccgatgccc tcttctggtg tgtctgaaga cagctacagt gtacttatat
      961 aataaacaaa taaatcttta aaaaaaaaaa caaaaacggg gctggagaga tggctcagcg
     1021 gttaagagcg cccgactgct cttccagagg tcatgagttc aattcccagc aaccacatgg
     1081 tggctcacaa ccatctgtaa agagatctga tgccctcttc tggtgtatct gaagacagct
     1141 acagtgtact tatatataat aaataaataa atctttaaaa aaaacaaaac aaaaacaaaa
     1201 acaaaacagt aatgacagag agtcacaagc tggtccctca gtgactacct ttcctccagg
     1261 agcgtgccta cattcccgag ggacagcgct attccattca gaatgcccag gctgcgttct
     1321 gcttctcaga gaccatccca gcccccaccg gcaaggagga ggcccagcag agaactgtga
     1381 gtaggcccag gccttgtctg tacagatcct cttttcttcc caagcagccc taactgcagt
     1441 ccaggccagg gaccagctct tccctgaggc tgaggtaacc tgggagtccc aggcagaggt
     1501 cactagctaa tgcacagccc cttttttccc tcaggacatg gaattgcttc gcttctcgct
     1561 gctgctcatc cagtcatggc tggggcccgt gcagtttctc agcaggatct ttaccaacag
     1621 cctgatgttt ggtacctcgg accgcgtcta tgagaaactg aaggacctgg aagagggcat
     1681 ccaggctctg atgcaggtca ggatggaccg ggggcgctag cctgaggtta tactgacctt
     1741 tgcctctgct tggagcctag ctggggggct cactgagctc tgtttaccgg tcagacctta
     1801 aaccttgaga aggcttccta ctcactttcc cttatgaagc ctccaggcct ttctctaggt
     1861 tctggagttg gggagggcac ggctctgagt tcttctttcc cacaacagga gctggaagac
     1921 ggcagccccc gtattgggca gatcctcaag caaacctatg acaagtttga cgccaacatg
     1981 cgcagcgatg acgctctgct caaaaactat gggctgctct cctgcttcaa gaaggacctg
     2041 cacaaggcag agacctacct gcgggtcatg aagtgtcgcc gctttgcgga aagcagctgt
     2101 gctttctagg cacacactgg tgtctctgcg gcactccccc gttacccccc tgtactctgg
     2161 caactgccac ccctacactt tgtcctaata aaattaagat gcatcatatc actctgctag
     2221 acatcttttt tttttttgaa ggc
//