Path: utzoo!utgpu!watserv1!watmath!att!news.cs.indiana.edu!bionet!will
From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Chicken gene for myosin light chain (exons 2-4)
Message-ID: <May.28.12.02.06.1991.12049@genbank.bio.net>
Date: 28 May 91 19:02:07 GMT
Sender: will@genbank.bio.net
Distribution: bionet
Lines: 76
Approved: lear@genbank.bio.net
Checksum: 35934     4

LOCUS       CHKMY04      1365 bp ds-DNA             VRT       28-MAY-1991
DEFINITION  Chicken gene for myosin light chain (exons 2-4)
ACCESSION   X00459
KEYWORDS    alternate splicing; myosin.
SOURCE      Gallus gallus DNA.
  ORGANISM  Gallus gallus
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Aves;
            Neornithes; Neognathae; Galliformes; Phasianidae.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Nabeshima,Y., Fujii-Kuriyama,Y., Muramatsu,M. and Ogata,K.
  TITLE     Alternative transcription and two modes of splicing result in two
            myosin light chains from one gene
  JOURNAL   Nature 308, 333-338 (1984)
  STANDARD  full automatic
COMMENT     EPD; 07064; Gg myosin LC3.
            
            This represents the first report of a cellular gene which produces
            two polypeptides from a single gene by differential initiation of
            transcription followed by a different mode of splicing.(see x00458)
            LC1 mRNA: exons 1,4,5,6,7,8,9 LC3 mRNA: exons 2,3,5,6,7,8,9 also
            see <GGMY03> and <GGMY05>
            
            From EMBL    entry GGMY04;  dated 06-JUL-1989.
FEATURES             Location/Qualifiers
     intron          <1..347
                     /note="intron 1"
     promoter        318..325
                     /note="promoter structure"
     mRNA            348..421
                     /note="exon 2"
     CDS             419..421
                     /note="myosin light chain part 2"
                     /codon_start=419
     intron          422..998
                     /note="intron 2"
     mRNA            999..1023
                     /note="exon 3"
     CDS             999..1023
                     /note="myosin light chain part 3"
                     /codon_start=999
     intron          1024..1269
                     /note="intron 3"
     mRNA            1270..1297
                     /note="exon 4"
     CDS             1270..1297
                     /note="myosin light chain part 4 (1297 is 1st base in
                     codon)"
                     /codon_start=1270
     intron          1298..>1365
                     /note="intron 4 (1023 is 1st base in codon)"
BASE COUNT      374 a    318 c    310 g    362 t      1 others
ORIGIN
        1 acatggcacc tcattgccct cagcgctcct cgattgggga ctatagctta ttggagaaat
       61 aggagcctct cctatcatgg taggcccgga caaggaatat cccctcttga tggtccagac
      121 cccagaaagt gctgacatga tccaaacttg ctgcttgcaa ctcccttgcc cctctccaac
      181 ctcctaaaaa cagcagccga aaggcccatc aaggtacggt gccacctgtc actttgccca
      241 agaaagctag agaactcacc aaggggaggg gcagcttcct tctgacgcct aatccagcaa
      301 tgccgtcgcg ctgccagata aataagggga agaaaggcca ggaaagcagg accactctca
      361 gagacctctc agctaatcct ccggcccgtc cgccgctcta cttttccaac tctcaatcat
      421 ggtgggttca ctgcagacta aacgttagca gcgaggcagt gtattttaca gcagtaaatt
      481 cagcttcttg ttcaagttag tcctaggggg gaggataggc caagaggtga cagttcaggt
      541 ttgcttgatt ttcctctgaa tgtttttaat acaagagagt atcatagctt aaygctttat
      601 gaacaaaagc ttggaaggca tgatttattt tctatgttaa tgtttaaaaa gaaaaaaaaa
      661 aagaaaaaac ccgccaggta ttaaatatta cctcaaatgg gttggtattt gagtctatac
      721 taaagtatta agtgacctgg tggtacataa acaacctatt tgttaagaaa ctgtagatta
      781 ttagtgcttc tggccacaac cttgctgttc tcagggatgc aggtttttac aagagcccta
      841 aaaacaggcc tggggatgca tttttacatg gcaggttgcc agtttgggtt tctgtggcct
      901 aattacatca ggcaaggcag atatgggaat agctcagcac ctgtgcattt tcagcagtac
      961 tacttctcct ttttttcttt ctctcttccc aactgcagtc cttctcacct gacgaaatca
     1021 atggtaagtg aaacaaaaac taaactaaca gggggcagga ggggggaccg taacggctac
     1081 caaaaagcta aacgttcacc ggtcttaaga gctcttttgc catctgcatc acttctgtgc
     1141 atctgtcagg ccacggtttt tgctgtcttg gaagatactc atggattgag ctggatgctt
     1201 tagaaaacaa gcaggttctc ccccagcccc cccttcctaa gctatttttt gtgattgatt
     1261 tccgaccaga tcgagttctc caaggagcag caggatggta agttacaaga cagctgatgc
     1321 gtttgacatg tatgtgagtt cagaggggag ctacagtctt gaaag
//