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From: GenBank-Updates@genbank.bio.net
Newsgroups: bionet.molbio.genbank.updates
Subject: Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon
Message-ID: <May.30.05.09.24.1991.23751@genbank.bio.net>
Date: 30 May 91 12:09:24 GMT
Sender: root@genbank.bio.net
Distribution: bionet
Lines: 77
Approved: lear@genbank.bio.net
Checksum: 27854     5

LOCUS       HUMTAT12     1483 bp ds-DNA             PRI       30-MAY-1991
DEFINITION  Human gene for tyrosine aminotransferase (TAT) (EC 2.6.1.5) Exon
            12.
ACCESSION   X52519
KEYWORDS    aminotransferase; transferase; tyrosine aminotransferase.
SOURCE      Homo sapiens DNA.
  ORGANISM  Homo sapiens
            Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
            Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Scherer,G.
  JOURNAL   Unpublished (1990)
  STANDARD  full automatic
REFERENCE   2  (bases 1 to 1483)
  AUTHORS   Rettenmeier,R., Natt,E., Zentgraf,H. and Scherer,G.
  TITLE     Isolation and characterization of the human tyrosine
            aminotransferase gene
  JOURNAL   Nucleic Acids Res. 18, 3853-3861 (1990)
  STANDARD  full automatic
COMMENT     SWISS-PROT; P17735; ATTY$HUMAN.
            
            *source: tissue=placenta (genomic) and liver (cDNA); *source:
            library=genomic (phage) + cDNA; *source: clone=lambda-hTAT1,
            phcTAT3a-6; **map: chromosome=16q22.1; See <X52507>-<X52520>. Data
            kindly reviewed (26-JUL-1990) by Scherer G.
            
            From EMBL    entry HSTAT12;  dated 07-AUG-1990.
FEATURES             Location/Qualifiers
     intron          <1..20
                     /note="intron XI"
     mRNA            21..1454
                     /note="exon 12"
     CDS             21..158
                     /note="tyrosine aminotransferase (AA 409-454)"
                     /codon_start=21
     misc_feature    770..775
                     /note="minor mRNA polyadenylation signal"
     polyA_site      790..790
                     /note="minor mRNA polyadenylation site"
     repeat_region   816..830
                     /note="direct repeat flanking Alu element"
     misc_feature    complement(831..1179)
                     /note="Alu element"
     repeat_region   1180..1194
                     /note="direct repeat flanking Alu element"
     misc_feature    1438..1443
                     /note="major mRNA polyadenylation signal"
     polyA_site      1454..1454
                     /note="major mRNA polyadenylation site"
BASE COUNT      375 a    325 c    305 g    478 t
ORIGIN
        1 acagactctt ctttttgcag tgctttgagt acccgaattt catccgagtg gtcatcacag
       61 tccccgaggt gatgatgctg gaggcgtgca gccggatcca ggagttctgt gagcagcact
      121 accattgtgc tgaaggcagc caggaggagt gtgataaata ggcctgcatc cattctcctg
      181 aggatgtgtc ccatctaggg aaggctggac taggccttgc ggctcctcag ggactcaggt
      241 ggccctactg ggagaggggc ctcaaatgca ccatgtcaag ggttcaagat tgttcctgct
      301 tttccccaag tacaaccaca cccacactca gatcctcctc attcacatcg cagattactc
      361 ccttgctctg cgctgctaga gtgactcact aattcattaa tctgcctccc tctcgtaaga
      421 tttccttctt ttttttcttg aaagtaccag gtgaacaaag tttaccagaa agcagttgag
      481 acaagaaaat aagagctcag gatgagggaa aagaaaaaga ttgagagaat ttgtgccccc
      541 aaccatttcc tcagactcta agaaagaaca cgctctctcc aggcaggtct gaagctcaac
      601 tctcttattg cctcacttca ggtatacctc actttacaca atagaattat aactggaaag
      661 aagttgggga cacatgtatt tggtgattac attttaaaca cattaggaaa agttgctatt
      721 tgaacttttt attgattttt ggggggagta aagaattatt ttggatgcaa ataaatatcc
      781 tttaattgat cgacttgcca aatttagatt tgtgtgcatc aggctttctt ttttttcttt
      841 ttttagagaa gttcaatata agcttttctt ttctttgttt ctttctttct ttattttgag
      901 atggagtctt gctctgtcgc ccatgctgga gtgcagtggc gcgatctcgg ctcactgcaa
      961 cctccacctc ctgggttcaa gcgattctct tgcctcaacc tcccaagcag ttgggactac
     1021 aggcgtgagc caccatgccc ggctaatttt tgtattttta gtagagacag ggtttcacca
     1081 tgttagccag gctggtctca aactcctgac ctcaggcaat ctgcccgcct gggtctccta
     1141 aagtactggg attacaggcg tgagccacct cgcccagcgg catcaggctt tcttaaagtg
     1201 agagcacgcc tgtactagag caagcaggaa tcagagacct tccagaaata ctactgtgta
     1261 agggccagaa atatcttcac ttgtcattgt tatataatca ttattacttt tgctgtaatg
     1321 ttaatattga tttattaata tatattatct tttcatacat tttctaagaa acatttatat
     1381 tgataagatc ttttattttg caagggcata aattattgtt tttctttttt tttttttaat
     1441 aaatttcacc aagtatggct cttctgtgat gtgttttttt ctc
//