Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Posting-Version: version B 2.10.2 9/5/84; site reed.UUCP Path: utzoo!linus!decvax!tektronix!reed!alexis From: alexis@reed.UUCP (Alexis Dimitriadis) Newsgroups: net.bio Subject: Re: Human Genetics (a query) Message-ID: <1775@reed.UUCP> Date: Sun, 4-Aug-85 23:00:01 EDT Article-I.D.: reed.1775 Posted: Sun Aug 4 23:00:01 1985 Date-Received: Wed, 7-Aug-85 01:29:06 EDT References: <241@weitek.UUCP> Reply-To: alexis@reed.UUCP (Alexis Dimitriadis) Organization: Reed College, Portland, Oregon Lines: 43 Summary: In article <241@weitek.UUCP> mmm@weitek.UUCP (Mark Thorson) writes: > I have a question about biology that some netter should be able to > answer: Do human X and Y chromosomes recombine? I believe they don't. Recombination occurs between _homologous_ chromosomes, that is, chromosomes that are part of a "pair", and carry genes for the same traits. The X and Y chromosomes are completely different chromosomes. They do not pair up during meiosis, and thus no recombination events take place. It is a good thing they don't, because any recombination of parts that are not equivalent would almost certainly make the chromosome useless. (Imagine trading _part_of_ your gene for hemoglobin for part of a gene for eye color!) The Y chromosome is a very unusual chromosome: It is very small, and as far as anybody knows it has (almost) no identifiable genes on it. It is thought that the gene for having a hairy pinnae (sp), (part of the earlobe), may be on the Y chromosome, and one or two even odder things, but apart from those it does not code for any phenotypic characteristics. All the "sex linked" characters that you hear about in Biology class are on the X chromosome. > But do the sex chromosomes recombine? If they do, [...] > Sex would have to (?) be contained at one site > so it would be resistant to splitting via recombination. Note that as I implied above, recombination happens between arbitrary stretches of DNA, not in units of whole genes. A "sex gene" would not be resistant to recombination. At any rate, sex seems to be determined by regulatory mechanisms much more subtle than the possession of a particular gene. Remember, men carry all the genes that women carry. Alexis Dimitriadis -- _______________________________________________ As soon as I get a full time job, the opinions expressed above will attach themselves to my employer, who will never be rid of them again. alexis @ reed ...teneron! \ ...seismo!ihnp4! - tektronix! - reed.UUCP ...decvax! /