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From: emigh@ecsvax.UUCP (Ted Emigh)
Newsgroups: net.bio
Subject: Re: Malaria and sickle cell
Message-ID: <335@ecsvax.UUCP>
Date: Wed, 31-Dec-69 18:59:59 EDT
Article-I.D.: ecsvax.335
Posted: Wed Dec 31 18:59:59 1969
Date-Received: Sat, 31-Aug-85 03:42:55 EDT
References: <191@tekig5.UUCP> <314@kitty.UUCP> <678@cybvax0.UUCP> <1858@aecom.UUCP> <192@husky.uucp> <1868@aecoRe: Malaria and sickle cell <306@drutx.UUCP>
Reply-To: emigh@ecsvax.UUCP (Ted Emigh)
Organization: NC State University
Lines: 22
Summary: 

In article <306@drutx.UUCP> jca@drutx.UUCP (ArnsonJC) writes:
>It is not the HgbS that is responsible for malaria "immunity". It is
>due to lack of the Duffy Blood Group System genes, both a and b.
>[ie. Fya-, Fyb-].  It just happens that both the HgbS genes and
>Duffy {or should I say lack of} genes are both found in the same
>segment of the population. {Blacks}
>
>				jill

There are several polymorphisms thought to influence malaria resistance,
including Sickle Cell Anemia (HbS), Beta Thalassemia, G6PD deficiency, as
well as the Duffy trait.  It is possible for many genes to contribute to
disease resistance.  For more information consult: Human Genetics, by
Vogel and Motulsky.


-- 

Ted H. Emigh     Genetics and Statistics, North Carolina State U, Raleigh  NC
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