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From: werner@aecom.UUCP (Craig Werner)
Newsgroups: net.bio
Subject: Re: Re: anti RNA reverse transcriptase as HTLV therapy
Message-ID: <1941@aecom.UUCP>
Date: Sat, 12-Oct-85 01:36:33 EDT
Article-I.D.: aecom.1941
Posted: Sat Oct 12 01:36:33 1985
Date-Received: Mon, 14-Oct-85 05:07:06 EDT
References: <17@mit-amt.MIT.EDU> <622@bbncc5.UUCP>
Organization: Albert Einstein Coll. of Med., NY
Lines: 16


	When several months ago I posted the list of anti-AIDS drugs to
net.med, 5 out of 6 of the ones I mentioned were anti-reverse transcriptase
inhibitors (Reverse Transcriptase, which converts RNA to double stranded
DNA is found only in retroviruses.)
	The problems are 1) it only inhibits the virus, doesn't kill it, since
once the virus is established in humans, it doesn't need RT.
	and 2) the drugs have many side effects, including liver toxicity.
For instance, Rock Hudson almost died in France from liver failure caused by
the HPA-23 he was taking to slow AIDS.

-- 

				Craig Werner
				!philabs!aecom!werner
              "When I was your age, I did it for half an hour every day."