Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Posting-Version: version B 2.10.2 9/18/84; site bbncc5.UUCP Path: utzoo!linus!philabs!cmcl2!harvard!bbnccv!bbncc5!sdyer From: sdyer@bbncc5.UUCP (Steve Dyer) Newsgroups: net.motss,net.med,net.singles Subject: Re: Answer to AIDS questions Message-ID: <67@bbncc5.UUCP> Date: Fri, 22-Nov-85 01:42:07 EST Article-I.D.: bbncc5.67 Posted: Fri Nov 22 01:42:07 1985 Date-Received: Sat, 23-Nov-85 10:52:24 EST References: <3014@sun.uucp> Distribution: net Organization: Bolt Beranek and Newman, Cambridge, MA Lines: 22 Xref: linus net.motss:2033 net.med:2654 net.singles:8691 I think the advise to rely on agents containing nonoxynol-9 or, of all things, peroxide, is simply illadvised, bad folk-medicine, something we certainly don't need right now when it comes to AIDS. There are lots of agents which inactivate viruses in vitro, but which turn out to be ineffective or deleterious when used in vivo. I am repeating myself here (I addressed this several months ago) but Will's recommendations require this: There is no evidence that nonoxynol-9 spermicides or lubricants have any effect on the spread of HTLV-3 infection. Ditto for peroxide. Nonoxynol-9 is a detergent, and for all we know, it might facilitate its spread through some strange surface-active effect on mucous membranes. Peroxide is immediately broken down by catalase, ubiquitous in the body, and it's a weak antiseptic agent by any standards. The point is, we just don't know the effects of these (or any other) agents as prophylactic measures against infection, and it is downright irresponsible to give the impression that there is anything but uneducated guessing behind it. Better to not be exposed at all, by the use of condoms, TRUE safe-sex practices where there is no chance of exchanging fluids, or abstinence. -- /Steve Dyer {harvard,seismo}!bbnccv!bbncc5!sdyer sdyer@bbncc5.ARPA