Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Posting-Version: version B 2.10.2 9/17/84; site bcsaic.UUCP Path: utzoo!watmath!clyde!burl!ulysses!mhuxr!mhuxt!houxm!vax135!cornell!uw-beaver!ssc-vax!bcsaic!pamp From: pamp@bcsaic.UUCP (pam pincha) Newsgroups: net.bio,net.med,net.motss Subject: Re: AIDS Research - Antiviral Drugs (Query)? Message-ID: <413@bcsaic.UUCP> Date: Tue, 17-Dec-85 12:56:47 EST Article-I.D.: bcsaic.413 Posted: Tue Dec 17 12:56:47 1985 Date-Received: Thu, 19-Dec-85 04:15:59 EST References: <894@ecsvax.UUCP> <835@h-sc1.UUCP> Reply-To: pamp@bcsaic.UUCP (pam pincha) Distribution: net Organization: Boeing Computer Services AI Center, Seattle Lines: 40 Keywords: Also reverse transcriptase, and mosquitoes (???) Xref: watmath net.bio:323 net.med:2997 net.motss:2353 Summary: In article <835@h-sc1.UUCP> shiue@h-sc1.UUCP (steve shiue) writes: > > In addition, my roommate mentioned that mosquitoes might possibly >provide suitable vectors for the spread of the disease - I've heard that this >has been looked into in some towns in Florida with AIDS victims not in the >"high risk" groups. Does anyone know anything about this? Quote from Laurence,Jeffrey, 1985, The Immune system in AIDS, Scientific American,Dec.,vol.253,no.6,p.84-93. "The groups at highest risk for infection have become increasingly well defined; they include homosexual and bisexual men, abusers of injected drugs, the sexual partners of people in AIDS risk groups, and children born of mothers at risk. Recipients of blood transfusions and blood products have also contracted AIDS, but screening of donated blood for evidence of infection has drastically reduced their risk. The fact that the disease shows *NO SIGN* of spreading beyond those groups, except to predictable targets such as women who are artificially inseminated from infected donors, indicates that the virus is ONLY transmitted through the blood or through sexual intercourse. *ALL EPIDEMIOLOGIC EVIDENCE INDICATES THAT FOOD, WATER, INSECTS AND CASUAL CONTACT DO NO SPREAD AIDS." This is a good article on how this virus affects the immune system in great detail. The one thing of note that has come out of the studies is that it "appears that the total collapse of the immune defenses in AIDS victims stems largely from a single defect : a reduction in the number and a change in the function of the T4 lymphocytes, one of the many distinct kinds of cells that make upthe immune system." Some how it seem incrediable how the bodies defenses can collapse from the failure of just one element. P.M.Pincha-Wagener s