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From: davison@bnl44.UUCP (Dan Davison)
Newsgroups: net.bio,net.misc
Subject: Does aspirin inhibit oxidative phosphorylation?
Message-ID: <1038@bnl44.UUCP>
Date: Thu, 2-Jan-86 22:51:12 EST
Article-I.D.: bnl44.1038
Posted: Thu Jan  2 22:51:12 1986
Date-Received: Sun, 5-Jan-86 01:34:17 EST
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Xref: watmath net.bio:330 net.misc:9048


This is probably a tad esoteric, but have any net.bio'ers heard this before?

I was told some time ago (or possibly read) that high doses of aspirin
inhibit oxidative phosphorylation.

Is this true?

For arthritis-related reasons I sometimes take 5 or 6 aspirin at one time
(yes, I *know* that's a bad idea) but is the resulting fatigue due to my
mitochondria getting annoyed?

thanks in advance,
dan davison
uucp...decvax!philabs!sbcs!bnl44!davison
bitnet bchs6 at uhupvm1.bitnet
arpa: davison at sumex-aim, davison at bnl44

and from the laws of the laboratory, the non-reciprocal laws of expectation:
positive expectations yield negative results
negative expectations yield negative results
...this happened to me throughout grad school (*sigh*, and now, too)