Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Path: utzoo!mnetor!seismo!columbia!rutgers!mit-eddie!genrad!panda!enmasse!drilex!axiom!linus!philabs!aecom!werner From: werner@aecom.UUCP (Craig Werner) Newsgroups: sci.med Subject: Re: sex and color Message-ID: <599@aecom.UUCP> Date: Fri, 14-Nov-86 02:20:37 EST Article-I.D.: aecom.599 Posted: Fri Nov 14 02:20:37 1986 Date-Received: Sun, 16-Nov-86 01:18:31 EST References: <2302@bucse.bu-cs.BU.EDU> <7858@tekecs.TEK.COM> <1229@cybvax0.UUCP> Organization: Albert Einstein Coll. of Med., NY Lines: 24 Summary: Sex Chromatin Bodies In article <1229@cybvax0.UUCP>, mrh@cybvax0.UUCP (Mike Huybensz) writes: > In article <7858@tekecs.TEK.COM> mikes@tekecs.TEK.COM (Michael Sellers) writes: > > If I remember correctly, the second X chromosome in females sits unused in > > the nucleus (it never "unbundles" in interphase like the rest of the > > chromosomes do). These are called "Barr bodies", after the guy who > > discovered them. When I took cytology, the professor, Leopold Koss, in a classic line, enjoined us about the following: "These are sex chromatin bodies, not Barr bodies. Barr had a collaborator [pause], whose name unfortunately escapes me at the time." BTW, they are officially Barr-Bertram bodies, and they were first described in the neurones of female cats. Also, it is thought that at least part of the 2nd X was active. At one point, I knew the exact band. But it has to be so, otherwise Turner's and Kleinfeldter's Syndrome patients would be normal, and they are not. -- Craig Werner (MD/PhD '91) !philabs!aecom!werner (1935-14E Eastchester Rd., Bronx NY 10461, 212-931-2517) "Why is it that half the calories is twice the price?"