Relay-Version: version B 2.10 5/3/83; site utzoo.UUCP Path: utzoo!mnetor!uunet!seismo!rutgers!sunybcs!boulder!eddy From: eddy@boulder.Colorado.EDU (Sean Eddy) Newsgroups: sci.bio,sci.med Subject: Acrylamide toxicity Message-ID: <1705@sigi.Colorado.EDU> Date: Thu, 30-Jul-87 10:34:17 EDT Article-I.D.: sigi.1705 Posted: Thu Jul 30 10:34:17 1987 Date-Received: Sat, 1-Aug-87 08:52:54 EDT Sender: news@sigi.Colorado.EDU Reply-To: eddy@boulder.Colorado.EDU (Sean Eddy) Distribution: world Organization: University of Colorado, Boulder Lines: 18 Xref: mnetor sci.bio:527 sci.med:2815 Acrylamide is used in biology labs as a gel for separating molecules by their size and charge. The liquid or solid powder form of acrylamide is a neurotoxin; supposedly the polymerized form is fairly inert. My question is this: does anyone know the mechanism of acrylamide toxicity? Most of my information is hearsay and likely to be inaccurate. For instance, is it true that acrylamide poisoning is irreversible? What nerves, if not all, does it affect? etc., etc. Thanks, - Sean Eddy - MCD Biology; U. of Colorado at Boulder; Boulder CO 80309 - eddy@boulder.colorado.EDU !{hao,nbires}!boulder!eddy - - "On second thought, let's not go to Camelot. 'Tis a silly place."